Interactor 1: THIC (Q9BWD1)
Acetyl-CoA acetyltransferase, cytosolic (EC 2.3.1.9) (Acetyl-CoA transferase-like protein) (Cytosolic acetoacetyl-CoA thiolase)
Gene: ACAT2

Interactor 2: THIC (Q9BWD1)
Acetyl-CoA acetyltransferase, cytosolic (EC 2.3.1.9) (Acetyl-CoA transferase-like protein) (Cytosolic acetoacetyl-CoA thiolase)
Gene: ACAT2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.791

The method score is based on:

Property Details
Experiments 25416956, 21988832
Identification Methods two hybrid, two hybrid array
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Thiolase_C~Thiolase_C, Thiolase_C~Thiolase_N, Thiolase_N~Thiolase_N
Common GO terms GO:0003985 - acetyl-CoA C-acetyltransferase activity
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005829 - cytosol
GO:0006629 - lipid metabolic process
and 3 others

more...

Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 397
Hs

1 397
+ Hs
+ At
+ Hs
+ Ec
+ Sc
+ Sc
+ Mt

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024