HitPredict

Interactor 1: CDK19 (Q9BWU1)
Cyclin-dependent kinase 19 (EC 2.7.11.22) (CDC2-related protein kinase 6) (Cell division cycle 2-like protein kinase 6) (Cell division protein kinase 19) (Cyclin-dependent kinase 11) (Death-preventing kinase)
Gene: CDK19

Interactor 2: MED28 (Q9H204)
Mediator of RNA polymerase II transcription subunit 28 (Endothelial-derived protein 1) (Mediator complex subunit 28) (Merlin and Grb2-interacting cytoskeletal protein) (Magicin) (Tumor angiogenesis marker EG-1)
Gene: MED28

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.93	0.60	0.749

Property	Details
Experiments	15175163, 33961781, 35271311, 20133760, 26186194, 28514442, 24981860, 23602568
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 502 Hs			1 178
+	Hs
		826355 CDK8_HUMAN (1-502): 1.77e-150: 439: 76.69		MED28_HUMAN (1-178): 5.44e-109: 310: 100.00
+	Hs
		73041 B4DUB1_HUMAN (152-502): 1.59e-138: 406: 100.00		MED28_HUMAN (1-178): 5.44e-109: 310: 100.00