HitPredict

Interactor 1: CDK19 (Q9BWU1)
Cyclin-dependent kinase 19 (EC 2.7.11.22) (CDC2-related protein kinase 6) (Cell division cycle 2-like protein kinase 6) (Cell division protein kinase 19) (Cyclin-dependent kinase 11) (Death-preventing kinase)
Gene: CDK19

Interactor 2: MED31 (Q9Y3C7)
Mediator of RNA polymerase II transcription subunit 31 (Mediator complex subunit 31) (Mediator complex subunit SOH1) (hSOH1)
Gene: MED31

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.93	0.60	0.750

Property	Details
Experiments	24981860, 35271311, 26186194, 28514442, 33961781, 32707033, 23602568
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 502 Hs			1 131
+	Hs
		826381 CDK8_HUMAN (1-502): 1.77e-150: 439: 76.69		MED31_HUMAN (1-131): 4.08e-63: 190: 100.00
+	Hs
		73051 B4DUB1_HUMAN (152-502): 1.59e-138: 406: 100.00		MED31_HUMAN (1-131): 4.08e-63: 190: 100.00
+	Hs
		841364 CDK7_HUMAN (27-354): 7.4e-56: 191: 38.21		MED31_HUMAN (1-131): 4.08e-63: 190: 100.00
+	Sc
		751464 SSN3_YEAST (41-376): 4.15e-75: 248: 43.64		MED31_YEAST (3-79): 2.86e-26: 97: 43.59