HitPredict

Interactor 1: SSBP3 (Q9BWW4)
Single-stranded DNA-binding protein 3 (Sequence-specific single-stranded-DNA-binding protein)
Gene: SSBP3

Interactor 2: LHX6 (Q9UPM6)
LIM/homeobox protein Lhx6 (LIM homeobox protein 6) (LIM/homeobox protein Lhx6.1)
Gene: LHX6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.60	0.699

Property	Details
Experiments	26186194, 28514442, 33961781, 35140242
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 388 Hs			1 363
+	Hs
		1148491 SSBP3_HUMAN (1-388): 5.14e-67: 218: 100.00		LHX8_HUMAN (8-348): 4.5e-61: 201: 51.30
+	Hs
		238119 SSBP3_HUMAN (1-388): 5.14e-67: 218: 100.00		LMX1B_HUMAN (29-343): 5.52e-59: 197: 26.11
+	Mm
		292011 SSBP3_MOUSE (1-388): 5.14e-67: 218: 100.00		LMX1B_MOUSE (29-338): 9.66e-59: 196: 26.51
+	Hs
		899933 SSBP3_HUMAN (1-388): 5.14e-67: 218: 100.00		ISL1_HUMAN (60-360): 3.14e-56: 189: 26.94
+	Mm
		899944 SSBP3_MOUSE (1-388): 5.14e-67: 218: 100.00		ISL1_MOUSE (60-360): 3.14e-56: 189: 26.94
+	Hs
		1314903 SSBP3_HUMAN (1-388): 5.14e-67: 218: 100.00		LHX9_HUMAN (8-344): 7.43e-55: 186: 24.03
+	Mm
		1321926 SSBP3_MOUSE (1-388): 5.14e-67: 218: 100.00		LHX9_MOUSE (8-344): 3.84e-54: 184: 24.03
+	Hs
		1283496 SSBP3_HUMAN (1-388): 5.14e-67: 218: 100.00		ISL2_HUMAN (61-343): 2.94e-53: 181: 28.05
+	Mm
		1321868 SSBP3_MOUSE (1-388): 5.14e-67: 218: 100.00		ISL2_MOUSE (61-343): 3.8e-53: 181: 28.05
+	Hs
		822674 SSBP3_HUMAN (1-388): 5.14e-67: 218: 100.00		LHX1_HUMAN (70-362): 1.71e-52: 180: 26.65
+	Hs
		238118 SSBP4_HUMAN (5-388): 9.47e-57: 192: 69.25		LMX1B_HUMAN (29-343): 5.52e-59: 197: 26.11
+	Hs
		839819 SSBP3_HUMAN (1-388): 5.14e-67: 218: 100.00		LHX2_HUMAN (27-199): 1.4e-47: 167: 34.46
+	Hs
		110821 SSBP3_HUMAN (1-388): 5.14e-67: 218: 100.00		H7C0H1_HUMAN (27-199): 3.62e-44: 158: 32.97
+	Mm
		1321929 SSBP3_MOUSE (1-388): 5.14e-67: 218: 100.00		LHX2_MOUSE (28-199): 1.55e-43: 156: 34.66
+	Hs
		822672 SSBP4_HUMAN (5-388): 9.47e-57: 192: 69.25		LHX1_HUMAN (70-362): 1.71e-52: 180: 26.65
+	Hs
		903773 SSBP3_HUMAN (1-388): 5.14e-67: 218: 100.00		LMO4_HUMAN (43-181): 2.86e-24: 99.4: 39.44
+	Hs
		1281179 SSBP3_HUMAN (1-388): 5.14e-67: 218: 100.00		LHX4_HUMAN (3-124): 3.11e-19: 90: 11.81
+	Hs
		1314910 SSBP3_HUMAN (1-388): 5.14e-67: 218: 100.00		LHX3_HUMAN (4-124): 2.09e-18: 87.7: 14.52
+	Hs
		638571 SSBP3_HUMAN (1-388): 5.14e-67: 218: 100.00		RBTN1_HUMAN (65-125): 1.45e-10: 61.1: 22.58
+	Hs
		638570 SSBP4_HUMAN (5-388): 9.47e-57: 192: 69.25		RBTN1_HUMAN (65-125): 1.45e-10: 61.1: 22.58