HitPredict

Interactor 1: JAM3 (Q9BX67)
Junctional adhesion molecule C (JAM-C) (JAM-2) (Junctional adhesion molecule 3) (JAM-3) [Cleaved into: Soluble form of JAM-C (sJAM-C)]
Gene: JAM3

Interactor 2: PICK1 (Q9NRD5)
PRKCA-binding protein (Protein interacting with C kinase 1) (Protein kinase C-alpha-binding protein)
Gene: PICK1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.67	0.60	0.636

Property	Details
Experiments	33961781, 15811349
Identification Methods	affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005794 - Golgi apparatus GO:0005886 - plasma membrane
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 310 Hs			1 415
+	Mm
		1143301 JAM3_MOUSE (25-310): 6.03e-64: 205: 86.71		PICK1_MOUSE (1-415): 0: 584: 94.47
+	Hs
		1344692 JAM1_HUMAN (14-310): 5.99e-58: 190: 31.21		PICK1_HUMAN (1-415): 0: 592: 100.00
+	Mm
		292318 JAM1_MOUSE (15-310): 2.09e-51: 173: 33.56		PICK1_MOUSE (1-415): 0: 584: 94.47
+	Hs
		883801 JAM2_HUMAN (39-310): 2.91e-43: 151: 36.63		PICK1_HUMAN (1-415): 0: 592: 100.00
+	Hs
		1298003 ROBO3_HUMAN (134-309): 5.15e-16: 80.7: 19.15		PICK1_HUMAN (1-415): 0: 592: 100.00
+	Hs
		609429 FGFR3_HUMAN (41-301): 1.07e-38: 146: 15.83		ICA1L_HUMAN (143-387): 1.08e-74: 242: 14.92