HitPredict

Interactor 1: JAM3 (Q9BX67)
Junctional adhesion molecule C (JAM-C) (JAM-2) (Junctional adhesion molecule 3) (JAM-3) [Cleaved into: Soluble form of JAM-C (sJAM-C)]
Gene: JAM3

Interactor 2: CLC4A (Q9UMR7)
C-type lectin domain family 4 member A (C-type lectin DDB27) (C-type lectin superfamily member 6) (Dendritic cell immunoreceptor) (Lectin-like immunoreceptor) (CD antigen CD367)
Gene: CLEC4A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0002250 - adaptive immune response GO:0005886 - plasma membrane
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 310 Hs			1 237
+	Hs
		1268547 PXDN_HUMAN (27-239): 9.9e-39: 147: 20.19		CLC4A_HUMAN (1-237): 9.8e-70: 215: 100.00
+	Hs
		609609 FGFR3_HUMAN (41-301): 1.07e-38: 146: 15.83		CLC4A_HUMAN (1-237): 9.8e-70: 215: 100.00
+	Hs
		1357318 ROBO1_HUMAN (22-239): 7.6e-37: 141: 19.91		CLC4A_HUMAN (1-237): 9.8e-70: 215: 100.00
+	Hs
		1166673 LRIG3_HUMAN (26-241): 1.3e-32: 129: 17.97		CLC4A_HUMAN (1-237): 9.8e-70: 215: 100.00
+	Hs
		1263883 LRIG1_HUMAN (25-310): 2.18e-38: 146: 17.69		CLC4D_HUMAN (31-237): 3.03e-54: 175: 33.33
+	Hs
		530196 NCAM1_HUMAN (18-306): 7.35e-25: 106: 12.91		CLC4A_HUMAN (1-237): 9.8e-70: 215: 100.00
+	Hs
		1031178 PTK7_HUMAN (31-231): 1.47e-23: 103: 16.51		CLC4A_HUMAN (1-237): 9.8e-70: 215: 100.00
+	Hs
		299599 LRIG2_HUMAN (26-241): 7.67e-34: 133: 19.82		CLC4E_HUMAN (25-236): 9.51e-58: 184: 34.58
+	Hs
		299573 LRIG2_HUMAN (26-241): 7.67e-34: 133: 19.82		CLC4D_HUMAN (31-237): 3.03e-54: 175: 33.33
+	Hs
		1100785 LRIG1_HUMAN (25-310): 2.18e-38: 146: 17.69		CL12B_HUMAN (1-232): 5.06e-45: 153: 17.82
+	Hs
		1271869 NEO1_HUMAN (26-245): 4.21e-16: 81.1: 9.69		CLC4A_HUMAN (1-237): 9.8e-70: 215: 100.00
+	Hs
		1031177 PTK7_HUMAN (31-231): 1.47e-23: 103: 16.51		CLC4E_HUMAN (25-236): 9.51e-58: 184: 34.58
+	Hs
		299565 LRIG2_HUMAN (26-241): 7.67e-34: 133: 19.82		CL12B_HUMAN (1-232): 5.06e-45: 153: 17.82
+	Hs
		644626 LRIG1_HUMAN (25-310): 2.18e-38: 146: 17.69		NKG2A_HUMAN (2-233): 1.65e-40: 140: 16.81
+	Hs
		1100734 LRIG3_HUMAN (26-241): 1.3e-32: 129: 17.97		CL12B_HUMAN (1-232): 5.06e-45: 153: 17.82
+	Hs
		149946 NCAM1_HUMAN (18-306): 7.35e-25: 106: 12.91		NCAN_HUMAN (86-232): 2.02e-47: 169: 27.33