HitPredict

Interactor 1: BTBD2 (Q9BX70)
BTB/POZ domain-containing protein 2
Gene: BTBD2

Interactor 2: CSN3 (Q9UNS2)
COP9 signalosome complex subunit 3 (SGN3) (Signalosome subunit 3) (JAB1-containing signalosome subunit 3)
Gene: COPS3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.694

Property	Details
Experiments	26186194, 28514442, 33961781, 19295130
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 525 Hs			1 423
+	Hs
		1327501 BTBD1_HUMAN (89-525): 1.79e-112: 344: 81.94		CSN3_HUMAN (1-423): 2.33e-144: 419: 100.00
+	Hs
		897304 BTBD2_HUMAN (1-525): 7.13e-128: 384: 100.00		CSN2_HUMAN (21-393): 1.28e-87: 275: 12.23
+	Hs
		897308 BTBD1_HUMAN (89-525): 1.79e-112: 344: 81.94		CSN2_HUMAN (21-393): 1.28e-87: 275: 12.23
+	Hs
		1311892 BTBD2_HUMAN (1-525): 7.13e-128: 384: 100.00		CSN4_HUMAN (1-397): 3.04e-62: 208: 15.87
+	Hs
		1311896 BTBD1_HUMAN (89-525): 1.79e-112: 344: 81.94		CSN4_HUMAN (1-397): 3.04e-62: 208: 15.87
+	Hs
		1120829 KLH12_HUMAN (366-517): 3.53e-30: 126: 9.80		CSN3_HUMAN (1-423): 2.33e-144: 419: 100.00
+	Hs
		1350484 KLH13_HUMAN (366-514): 1.89e-23: 106: 7.90		CSN3_HUMAN (1-423): 2.33e-144: 419: 100.00
+	Hs
		299535 KLH18_HUMAN (94-521): 1.49e-23: 106: 11.16		CSN3_HUMAN (1-423): 2.33e-144: 419: 100.00
+	Hs
		1153800 KLH10_HUMAN (328-517): 1.11e-22: 103: 7.33		CSN3_HUMAN (1-423): 2.33e-144: 419: 100.00
+	Hs
		1350341 KLHL8_HUMAN (365-460): 1.17e-13: 75.7: 13.40		CSN3_HUMAN (1-423): 2.33e-144: 419: 100.00
+	Hs
		897257 KLH12_HUMAN (366-517): 3.53e-30: 126: 9.80		CSN2_HUMAN (21-393): 1.28e-87: 275: 12.23
+	Hs
		299512 KLH18_HUMAN (94-521): 1.49e-23: 106: 11.16		CSN2_HUMAN (21-393): 1.28e-87: 275: 12.23
+	Hs
		897322 KLH13_HUMAN (366-514): 1.89e-23: 106: 7.90		CSN2_HUMAN (21-393): 1.28e-87: 275: 12.23
+	Hs
		897262 KLH10_HUMAN (328-517): 1.11e-22: 103: 7.33		CSN2_HUMAN (21-393): 1.28e-87: 275: 12.23
+	Hs
		897264 KLH24_HUMAN (321-515): 8e-19: 91.8: 11.33		CSN2_HUMAN (21-393): 1.28e-87: 275: 12.23
+	Hs
		897321 KLHL8_HUMAN (365-460): 1.17e-13: 75.7: 13.40		CSN2_HUMAN (21-393): 1.28e-87: 275: 12.23
+	Hs
		1120807 KLH12_HUMAN (366-517): 3.53e-30: 126: 9.80		CSN4_HUMAN (1-397): 3.04e-62: 208: 15.87
+	Hs
		1311911 KLH13_HUMAN (366-514): 1.89e-23: 106: 7.90		CSN4_HUMAN (1-397): 3.04e-62: 208: 15.87
+	Hs
		299532 KLH18_HUMAN (94-521): 1.49e-23: 106: 11.16		CSN4_HUMAN (1-397): 3.04e-62: 208: 15.87
+	Hs
		1153792 KLH10_HUMAN (328-517): 1.11e-22: 103: 7.33		CSN4_HUMAN (1-397): 3.04e-62: 208: 15.87