Interactor 1: NPL (Q9BXD5)
N-acetylneuraminate lyase (NALase) (EC 4.1.3.3) (N-acetylneuraminate pyruvate-lyase) (N-acetylneuraminic acid aldolase) (Sialate lyase) (Sialate-pyruvate lyase) (Sialic acid aldolase) (Sialic acid lyase)
Gene: NPL

Interactor 2: NPL (Q9BXD5)
N-acetylneuraminate lyase (NALase) (EC 4.1.3.3) (N-acetylneuraminate pyruvate-lyase) (N-acetylneuraminic acid aldolase) (Sialate lyase) (Sialate-pyruvate lyase) (Sialic acid aldolase) (Sialic acid lyase)
Gene: NPL

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.74 1.00 0.861

The method score is based on:

Property Details
Experiments 25416956, 32296183, unassigned1304
Identification Methods two hybrid, two hybrid array, two hybrid prey pooling approach, validated two hybrid
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains DHDPS~DHDPS
Common GO terms GO:0005829 - cytosol
GO:0005975 - carbohydrate metabolic process
GO:0008747 - N-acetylneuraminate lyase activity
GO:0019262 - N-acetylneuraminate catabolic process
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 320
Hs

1 320
+ At
+ Sp
+ Hs
+ Ec
+ Ec

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024