Interactor 1: PINK1 (Q9BXM7)
Serine/threonine-protein kinase PINK1, mitochondrial (EC 2.7.11.1) (BRPK) (PTEN-induced putative kinase protein 1)
Gene: PINK1

Interactor 2: PARL (Q9H300)
Presenilin-associated rhomboid-like protein, mitochondrial (EC 3.4.21.105) (Mitochondrial intramembrane cleaving protease PARL) [Cleaved into: P-beta (Pbeta)]
Gene: PARL

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 21355049
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0010821 - regulation of mitochondrion organization
GO:1903214 - regulation of protein targeting to mitochondrion
and 2 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 581
Hs

1 379
+ Dm
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024