HitPredict

Interactor 1: STK25 (O00506)
Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Ste20-like kinase) (Sterile 20/oxidant stress-response kinase 1) (SOK-1) (Ste20/oxidant stress response kinase 1)
Gene: STK25

Interactor 2: STRN3 (Q13033)
Striatin-3 (Cell cycle autoantigen SG2NA) (S/G2 antigen)
Gene: STRN3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.94	0.60	0.752

Property	Details
Experiments	26186194, 28514442, 18782753, 33961781, 35271311, 32707033, 23455922
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, pull down, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005794 - Golgi apparatus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 426 Hs			1 797
+	Hs
		1022891 STK24_HUMAN (8-424): 7.71e-143: 416: 71.12		STRN3_HUMAN (1-797): 0: 626: 100.00
+	Hs
		72974 B4DR80_HUMAN (10-416): 2.38e-139: 406: 68.46		STRN3_HUMAN (1-797): 0: 626: 100.00
+	Hs
		1022877 STK26_HUMAN (15-420): 4.41e-138: 403: 67.32		STRN3_HUMAN (1-797): 0: 626: 100.00
+	Hs
		1022843 Q8NBY1_HUMAN (15-420): 1.31e-131: 386: 64.29		STRN3_HUMAN (1-797): 0: 626: 100.00
+	Hs
		131539 STK25_HUMAN (1-426): 4.51e-156: 449: 100.00		STRN_HUMAN (19-797): 7.44e-179: 534: 62.45
+	Hs
		215296 STK24_HUMAN (8-424): 7.71e-143: 416: 71.12		STRN_HUMAN (19-797): 7.44e-179: 534: 62.45
+	Hs
		72970 B4DR80_HUMAN (10-416): 2.38e-139: 406: 68.46		STRN_HUMAN (19-797): 7.44e-179: 534: 62.45
+	Hs
		215282 STK26_HUMAN (15-420): 4.41e-138: 403: 67.32		STRN_HUMAN (19-797): 7.44e-179: 534: 62.45
+	Hs
		131609 STK25_HUMAN (1-426): 4.51e-156: 449: 100.00		STRN4_HUMAN (14-797): 2.83e-156: 475: 47.88
+	Hs
		215253 Q8NBY1_HUMAN (15-420): 1.31e-131: 386: 64.29		STRN_HUMAN (19-797): 7.44e-179: 534: 62.45
+	Rn
		936839 AKT3_RAT (2-344): 6.1e-132: 389: 23.08		STRN_RAT (19-797): 3.3e-176: 527: 62.60
+	Hs
		1344931 STK24_HUMAN (8-424): 7.71e-143: 416: 71.12		STRN4_HUMAN (14-797): 2.83e-156: 475: 47.88
+	Hs
		1344914 STK26_HUMAN (15-420): 4.41e-138: 403: 67.32		STRN4_HUMAN (14-797): 2.83e-156: 475: 47.88
+	Hs
		1147013 STK24_HUMAN (8-424): 7.71e-143: 416: 71.12		A16L1_HUMAN (135-796): 5.19e-87: 289: 13.89
+	Dm
		87984 Q9VEN3_DROME (12-361): 1.06e-129: 389: 68.09		D3DML3_DROME (382-797): 1.67e-86: 292: 55.74
+	Hs
		616714 KS6B1_HUMAN (1-414): 5.17e-131: 389: 19.13		A16L1_HUMAN (135-796): 5.19e-87: 289: 13.89
+	Dm
		1213409 AKT1_DROME (13-334): 3.14e-131: 392: 24.47		NLE_DROME (495-796): 2.06e-58: 208: 15.56
+	At
		1105322 KIN10_ARATH (19-415): 1.47e-134: 397: 20.60		PRL1_ARATH (459-620): 3.56e-16: 84.1: 23.35
+	Hs
		863606 AKT3_HUMAN (2-344): 9.01e-134: 394: 23.36		COPA_HUMAN (483-759): 5.63e-15: 81.6: 22.95
+	At
		955193 KIN11_ARATH (1-415): 3.24e-132: 391: 20.14		PRL1_ARATH (459-620): 3.56e-16: 84.1: 23.35