HitPredict

Interactor 1: AP1M1 (Q9BXS5)
AP-1 complex subunit mu-1 (AP-mu chain family member mu1A) (Adaptor protein complex AP-1 subunit mu-1) (Adaptor-related protein complex 1 subunit mu-1) (Clathrin assembly protein complex 1 mu-1 medium chain 1) (Clathrin coat assembly protein AP47) (Clathrin coat-associated protein AP47) (Golgi adaptor HA1/AP1 adaptin mu-1 subunit) (Mu-adaptin 1) (Mu1A-adaptin)
Gene: AP1M1

Interactor 2: SAR1B (Q9Y6B6)
Small COPII coat GTPase SAR1B (EC 3.6.5.2) (GTP-binding protein B) (GTBPB) (Secretion-associated Ras-related GTPase 1B)
Gene: SAR1B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Adap_comp_sub~Arf
Common GO terms	GO:0005765 - lysosomal membrane GO:0005829 - cytosol GO:0006886 - intracellular protein transport
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 423 Hs			1 198
+	Hs
		119710 AP4M1_HUMAN (3-422): 3.59e-119: 356: 25.83		ARF5_HUMAN (10-197): 5.28e-75: 225: 27.66
+	Hs
		119709 AP4M1_HUMAN (3-422): 3.59e-119: 356: 25.83		ARF1_HUMAN (1-197): 1.8e-59: 185: 26.90
+	Hs
		1344237 STON1_HUMAN (125-423): 9.89e-68: 230: 19.43		SAR1A_HUMAN (1-198): 8.78e-63: 194: 89.90
+	Hs
		818920 COPD_HUMAN (8-165): 1.23e-18: 89.7: 17.72		ARF5_HUMAN (10-197): 5.28e-75: 225: 27.66
+	Hs
		574618 COPD_HUMAN (8-165): 1.23e-18: 89.7: 17.72		ARF4_HUMAN (10-197): 2.61e-74: 223: 27.66
+	Hs
		818916 COPD_HUMAN (8-165): 1.23e-18: 89.7: 17.72		ARF6_HUMAN (21-196): 3.66e-74: 222: 30.11
+	Hs
		818911 COPD_HUMAN (8-165): 1.23e-18: 89.7: 17.72		ARF3_HUMAN (8-197): 1.62e-62: 193: 27.90
+	Hs
		818919 COPD_HUMAN (8-165): 1.23e-18: 89.7: 17.72		ARF1_HUMAN (1-197): 1.8e-59: 185: 26.90