HitPredict

Interactor 1: MLP3C (Q9BXW4)
Microtubule-associated proteins 1A/1B light chain 3C (Autophagy-related protein LC3 C) (Autophagy-related ubiquitin-like modifier LC3 C) (MAP1 light chain 3-like protein 3) (MAP1A/MAP1B light chain 3 C) (MAP1A/MAP1B LC3 C) (Microtubule-associated protein 1 light chain 3 gamma)
Gene: MAP1LC3C

Interactor 2: AMRA1 (Q9C0C7)
Activating molecule in BECN1-regulated autophagy protein 1 (DDB1- and CUL4-associated factor 3)
Gene: AMBRA1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.27	0.60	0.408

Property	Details
Experiments	30217973
Identification Methods	unspecified method
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000045 - autophagosome assembly GO:0005776 - autophagosome GO:0005829 - cytosol GO:0009267 - cellular response to starvation GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 147 Hs			1 1298
+	Hs
		306305 GBRAP_HUMAN (13-127): 3.44e-54: 168: 38.26		AMRA1_HUMAN (1-1298): 0: 1603: 100.00
+	Hs
		891308 GBRL2_HUMAN (13-126): 1.65e-54: 168: 42.98		AMRA1_HUMAN (1-1298): 0: 1603: 100.00
+	Hs
		1319005 MLP3A_HUMAN (7-126): 2.49e-53: 165: 59.17		AMRA1_HUMAN (1-1298): 0: 1603: 100.00
+	Hs
		1319001 MLP3B_HUMAN (7-127): 8.15e-53: 164: 54.55		AMRA1_HUMAN (1-1298): 0: 1603: 100.00
+	Hs
		1319003 GBRL1_HUMAN (13-126): 4.75e-52: 162: 39.47		AMRA1_HUMAN (1-1298): 0: 1603: 100.00
+	Hs
		891030 GBRL2_HUMAN (13-126): 1.65e-54: 168: 42.98		WDR5_HUMAN (3-297): 2.47e-87: 289: 18.39