HitPredict

Interactor 1: MLP3C (Q9BXW4)
Microtubule-associated proteins 1A/1B light chain 3C (Autophagy-related protein LC3 C) (Autophagy-related ubiquitin-like modifier LC3 C) (MAP1 light chain 3-like protein 3) (MAP1A/MAP1B light chain 3 C) (MAP1A/MAP1B LC3 C) (Microtubule-associated protein 1 light chain 3 gamma)
Gene: MAP1LC3C

Interactor 2: ATG10 (Q9H0Y0)
Ubiquitin-like-conjugating enzyme ATG10 (EC 2.3.2.-) (Autophagy-related protein 10) (APG10-like)
Gene: ATG10

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	20562859
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000045 - autophagosome assembly GO:0005829 - cytosol GO:0016236 - macroautophagy
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 147 Hs			1 220
+	Hs
		306312 GBRAP_HUMAN (13-127): 3.44e-54: 168: 38.26		ATG10_HUMAN (1-220): 4.65e-112: 321: 100.00
+	Hs
		891316 GBRL2_HUMAN (13-126): 1.65e-54: 168: 42.98		ATG10_HUMAN (1-220): 4.65e-112: 321: 100.00
+	Hs
		1326136 MLP3B_HUMAN (7-127): 8.15e-53: 164: 54.55		ATG10_HUMAN (1-220): 4.65e-112: 321: 100.00
+	Hs
		1328025 GBRL1_HUMAN (13-126): 4.75e-52: 162: 39.47		ATG10_HUMAN (1-220): 4.65e-112: 321: 100.00
+	Hs
		61902 MP3B2_HUMAN (7-127): 1.01e-51: 162: 53.72		ATG10_HUMAN (1-220): 4.65e-112: 321: 100.00
+	Mm
		1246814 MLP3B_MOUSE (7-126): 6.48e-53: 165: 55.00		ATG10_MOUSE (3-216): 8.99e-107: 307: 80.84
+	Hs
		1315807 MLP3C_HUMAN (1-147): 4.64e-72: 214: 100.00		ATG3_HUMAN (54-210): 5.45e-52: 171: 18.63
+	At
		1013368 ATG8F_ARATH (9-126): 2.14e-58: 178: 42.37		ATG3_ARATH (34-209): 5.8e-57: 184: 13.26
+	Hs
		306334 GBRAP_HUMAN (13-127): 3.44e-54: 168: 38.26		ATG3_HUMAN (54-210): 5.45e-52: 171: 18.63
+	Hs
		891336 GBRL2_HUMAN (13-126): 1.65e-54: 168: 42.98		ATG3_HUMAN (54-210): 5.45e-52: 171: 18.63
+	Hs
		1330642 MLP3A_HUMAN (7-126): 2.49e-53: 165: 59.17		ATG3_HUMAN (54-210): 5.45e-52: 171: 18.63
+	Mm
		1265087 MLP3A_MOUSE (7-126): 2.49e-53: 165: 59.17		ATG3_MOUSE (54-210): 2.12e-51: 170: 18.63
+	Hs
		1326176 MLP3B_HUMAN (7-127): 8.15e-53: 164: 54.55		ATG3_HUMAN (54-210): 5.45e-52: 171: 18.63
+	Hs
		1328043 GBRL1_HUMAN (13-126): 4.75e-52: 162: 39.47		ATG3_HUMAN (54-210): 5.45e-52: 171: 18.63
+	Hs
		61904 MP3B2_HUMAN (7-127): 1.01e-51: 162: 53.72		ATG3_HUMAN (54-210): 5.45e-52: 171: 18.63
+	Ce
		999358 LGG1_CAEEL (12-126): 1.46e-52: 164: 38.26		Q9N369_CAEEL (70-211): 1.12e-42: 147: 23.45
+	Ce
		1095400 LGG2_CAEEL (10-126): 1.88e-44: 143: 47.01		Q9N369_CAEEL (70-211): 1.12e-42: 147: 23.45
+	Pf
		83078 Q8IJK2_PLAF7 (10-126): 2.29e-46: 148: 36.51		C0H519_PLAF7 (88-209): 1.91e-37: 134: 21.60
+	Sc
		745998 ATG8_YEAST (11-126): 1.29e-54: 169: 38.79		ATG3_YEAST (39-209): 1.69e-26: 105: 13.30