Interactor 1: FACD2 (Q9BXW9)
Fanconi anemia group D2 protein (Protein FACD2)
Gene: FANCD2

Interactor 2: FANCI (Q9NVI1)
Fanconi anemia group I protein (Protein FACI)
Gene: FANCI

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.988

The method score is based on:

Property Details
Experiments 25862789, 21719678, 25168188, 25319828, 28684355, 28575658, 32510829, 33795880, 34469738, 36385258, 19561358, 18931676, 17460694, 24623813, 27773793, 24794430, 25489943, 23993743, 30456385, 31180492 and 2 others

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Identification Methods affinity chromatography technology, fluorescent resonance energy transfer, pull down, two hybrid, x-ray crystallography, biochemical, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains FANCI_HD2~FancD2, FANCI_S1~FancD2, FANCI_S1-cap~FancD2, FANCI_S2~FancD2, FANCI_S4~FancD2
Common GO terms GO:0000785 - chromatin
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0036297 - interstrand cross-link repair
GO:0070182 - DNA polymerase binding
and 1 others

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Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 1451
Hs

1 1328
+ Mm
+ Gg
+ Xl

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024