Interactor 1: RSPO3 (Q9BXY4)
R-spondin-3 (Protein with TSP type-1 repeat) (hPWTSR) (Roof plate-specific spondin-3) (hRspo3) (Thrombospondin type-1 domain-containing protein 2)
Gene: RSPO3

Interactor 2: ZNRF3 (Q9ULT6)
E3 ubiquitin-protein ligase ZNRF3 (EC 2.3.2.27) (RING finger protein 203) (RING-type E3 ubiquitin transferase ZNRF3) (Zinc/RING finger protein 3)
Gene: ZNRF3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.71 1.00 0.845

The method score is based on:

Property Details
Experiments 24050775, 25504990, 29752411
Identification Methods fluorescent resonance energy transfer, pull down
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Furin-like_2~ZNRF_3_ecto
Common GO terms GO:0005109 - frizzled binding
Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 272
Hs

1 936
+ Hs
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+ Mm
+ Xl
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024