HitPredict

Interactor 1: PACN1 (Q9BY11)
Protein kinase C and casein kinase substrate in neurons protein 1 (Syndapin-1)
Gene: PACSIN1

Interactor 2: TARA (Q9H2D6)
TRIO and F-actin-binding protein (Protein Tara) (TRF1-associated protein of 68 kDa) (Trio-associated repeat on actin)
Gene: TRIOBP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	PH~SH3_9
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 444 Hs			1 2365
+	Hs
		1329256 PACN2_HUMAN (1-444): 2.16e-80: 258: 61.32		TARA_HUMAN (1-2365): 4.78e-172: 589: 100.00
+	Hs
		1329254 PACN3_HUMAN (7-444): 2.52e-76: 246: 49.32		TARA_HUMAN (1-2365): 4.78e-172: 589: 100.00
+	Hs
		1167415 PACN1_HUMAN (1-444): 6.15e-95: 294: 100.00		MPRIP_HUMAN (1554-2357): 2.27e-56: 217: 33.82
+	Hs
		1167445 PACN2_HUMAN (1-444): 2.16e-80: 258: 61.32		MPRIP_HUMAN (1554-2357): 2.27e-56: 217: 33.82
+	Hs
		1167441 PACN3_HUMAN (7-444): 2.52e-76: 246: 49.32		MPRIP_HUMAN (1554-2357): 2.27e-56: 217: 33.82
+	Hs
		207844 PPIP1_HUMAN (10-444): 1.02e-62: 210: 19.77		MYH13_HUMAN (1524-2365): 2.97e-45: 183: 8.91
+	Hs
		725061 PACN3_HUMAN (7-444): 2.52e-76: 246: 49.32		MYH9_HUMAN (1312-2225): 5.12e-28: 126: 8.32
+	Hs
		207766 PPIP1_HUMAN (10-444): 1.02e-62: 210: 19.77		DESP_HUMAN (1531-2365): 6.57e-16: 86.9: 10.21
+	Hs
		724794 FCHO2_HUMAN (10-411): 5.55e-44: 166: 16.26		MYH9_HUMAN (1312-2225): 5.12e-28: 126: 8.32
+	Hs
		1078856 ITSN1_HUMAN (367-442): 5.46e-13: 73.6: 31.58		MYH14_HUMAN (2035-2363): 1.9e-15: 85.4: 15.06