HitPredict

Interactor 1: EIF2A (Q9BY44)
Eukaryotic translation initiation factor 2A (eIF-2A) (65 kDa eukaryotic translation initiation factor 2A) [Cleaved into: Eukaryotic translation initiation factor 2A, N-terminally processed]
Gene: EIF2A

Interactor 2: PKHA4 (Q9H4M7)
Pleckstrin homology domain-containing family A member 4 (PH domain-containing family A member 4) (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1)
Gene: PLEKHA4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31091453
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 585 Hs			1 779
+	Hs
		879342 EIF3B_HUMAN (14-517): 1.45e-87: 290: 17.53		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		1318178 TBL1R_HUMAN (154-420): 2.78e-35: 141: 12.41		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		1319411 WDR33_HUMAN (2-201): 2.68e-29: 126: 9.57		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		1309164 TBL1Y_HUMAN (87-419): 1.01e-22: 103: 14.60		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		793030 LIS1_HUMAN (310-529): 2.68e-16: 83.3: 13.51		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		1313650 KTNB1_HUMAN (2-141): 5.48e-15: 80.2: 11.27		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		903516 WDR5_HUMAN (303-449): 6.77e-15: 77.9: 14.09		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		1016326 TBL3_HUMAN (273-459): 4.7e-12: 71: 8.67		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		1331436 NLE1_HUMAN (355-490): 1.49e-10: 65.6: 8.09		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Sc
		410105 EIF3B_YEAST (14-500): 5.79e-101: 324: 15.37		OSH1_YEAST (2-550): 5.4e-39: 158: 10.80
+	Hs
		879271 EIF3B_HUMAN (14-517): 1.45e-87: 290: 17.53		PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02
+	Hs
		879297 EIF3B_HUMAN (14-517): 1.45e-87: 290: 17.53		RHG24_HUMAN (55-181): 6.43e-27: 119: 25.93
+	Hs
		1153371 TBL1R_HUMAN (154-420): 2.78e-35: 141: 12.41		PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02
+	Hs
		1022446 WDR33_HUMAN (2-201): 2.68e-29: 126: 9.57		TIAM1_HUMAN (2-634): 3.43e-44: 174: 12.28
+	Hs
		903302 WDR5_HUMAN (303-449): 6.77e-15: 77.9: 14.09		PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02
+	Hs
		1016298 TBL3_HUMAN (273-459): 4.7e-12: 71: 8.67		RHG24_HUMAN (55-181): 6.43e-27: 119: 25.93
+	Hs
		787153 TBL3_HUMAN (273-459): 4.7e-12: 71: 8.67		RHG25_HUMAN (30-181): 1.01e-21: 102: 23.27