HitPredict

Interactor 1: STK25 (O00506)
Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Ste20-like kinase) (Sterile 20/oxidant stress-response kinase 1) (SOK-1) (Ste20/oxidant stress response kinase 1)
Gene: STK25

Interactor 2: PHOCN (Q9Y3A3)
MOB-like protein phocein (2C4D) (Class II mMOB1) (Mob1 homolog 3) (Mob3) (Mps one binder kinase activator-like 3) (Preimplantation protein 3)
Gene: MOB4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.60	0.699

Property	Details
Experiments	18782753, 37536630, 32707033, 23455922
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation, pull down, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005794 - Golgi apparatus GO:0046872 - metal ion binding
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 426 Hs			1 225
+	Hs
		1377585 STK24_HUMAN (8-424): 7.71e-143: 416: 71.12		PHOCN_HUMAN (1-225): 8.34e-111: 318: 100.00
+	Hs
		1350187 STK26_HUMAN (15-420): 4.41e-138: 403: 67.32		PHOCN_HUMAN (1-225): 8.34e-111: 318: 100.00
+	Hs
		1350192 STK26_HUMAN (15-420): 4.41e-138: 403: 67.32		S4R3N1_HUMAN (14-225): 1.29e-103: 301: 97.64
+	Hs
		1027459 STK3_HUMAN (2-295): 3.42e-128: 380: 51.01		PHOCN_HUMAN (1-225): 8.34e-111: 318: 100.00
+	Hs
		1023145 STK4_HUMAN (3-284): 1.11e-127: 379: 52.80		PHOCN_HUMAN (1-225): 8.34e-111: 318: 100.00
+	Dm
		1178607 Q9VEN3_DROME (12-361): 1.06e-129: 389: 68.09		MOB4_DROME (1-225): 1.36e-105: 305: 80.00
+	Dm
		1178598 HIPPO_DROME (3-385): 3.61e-120: 366: 39.79		MOB4_DROME (1-225): 1.36e-105: 305: 80.00
+	Hs
		1027394 STK3_HUMAN (2-295): 3.42e-128: 380: 51.01		MOB3B_HUMAN (20-212): 5.12e-91: 268: 20.40
+	Hs
		1027437 STK3_HUMAN (2-295): 3.42e-128: 380: 51.01		MOB1A_HUMAN (17-212): 4.06e-89: 263: 20.10
+	Hs
		1023117 STK4_HUMAN (3-284): 1.11e-127: 379: 52.80		MOB1A_HUMAN (17-212): 4.06e-89: 263: 20.10
+	Hs
		1027391 STK3_HUMAN (2-295): 3.42e-128: 380: 51.01		MOB1B_HUMAN (19-212): 8.58e-88: 259: 20.30
+	Hs
		1023070 STK4_HUMAN (3-284): 1.11e-127: 379: 52.80		MOB1B_HUMAN (19-212): 8.58e-88: 259: 20.30
+	Dm
		1249830 HIPPO_DROME (3-385): 3.61e-120: 366: 39.79		MOB1_DROME (22-212): 2.97e-86: 256: 21.68
+	Hs
		1026924 PAK2_HUMAN (1-295): 4.19e-120: 361: 42.09		MOB3C_HUMAN (19-217): 1.08e-87: 259: 17.87
+	Mm
		949324 TNIK_MOUSE (15-293): 4.43e-72: 248: 45.97		PHOCN_MOUSE (1-225): 8.34e-111: 318: 100.00
+	Hs
		1356420 TNIK_HUMAN (15-293): 6.7e-72: 247: 45.97		PHOCN_HUMAN (1-225): 8.34e-111: 318: 100.00
+	Dm
		1178592 Q7KV89_DROME (15-322): 5.92e-73: 249: 44.99		MOB4_DROME (1-225): 1.36e-105: 305: 80.00
+	Dm
		56110 A1ZBH7_DROME (12-270): 1.53e-74: 254: 49.44		MOB1_DROME (22-212): 2.97e-86: 256: 21.68