HitPredict

Interactor 1: SHAN3 (Q9BYB0)
SH3 and multiple ankyrin repeat domains protein 3 (Shank3) (Proline-rich synapse-associated protein 2) (ProSAP2)
Gene: SHANK3

Interactor 2: SRCN1 (Q9C0H9)
SRC kinase signaling inhibitor 1 (SNAP-25-interacting protein) (SNIP) (p130Cas-associated protein) (p140Cap)
Gene: SRCIN1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	36950384
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0014069 - postsynaptic density GO:0061001 - regulation of dendritic spine morphogenesis
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1731 Hs			1 1183
+	Mm
		1116149 SHAN3_MOUSE (1-1731): 8.04e-176: 579: 93.71		SRCN1_MOUSE (2-1183): 0: 1537: 89.32
+	Mm
		1194594 SHAN2_MOUSE (356-1728): 4.66e-97: 348: 35.75		SRCN1_MOUSE (2-1183): 0: 1537: 89.32
+	Mm
		970500 ANK1_MOUSE (89-1027): 8.01e-71: 266: 11.20		SRCN1_MOUSE (2-1183): 0: 1537: 89.32
+	Mm
		103612 ANK3_MOUSE (120-691): 8.6e-55: 214: 14.98		SRCN1_MOUSE (2-1183): 0: 1537: 89.32
+	Hs
		965146 ANK2_HUMAN (117-358): 6.7e-53: 208: 25.27		SRCN1_HUMAN (1-1183): 0: 1528: 100.00
+	Mm
		88378 SHAN1_MOUSE (323-1726): 7.25e-25: 115: 13.87		SRCN1_MOUSE (2-1183): 0: 1537: 89.32
+	Mm
		1208056 ANK2_MOUSE (134-336): 2.34e-09: 65.1: 29.56		SRCN1_MOUSE (2-1183): 0: 1537: 89.32
+	Hs
		1021413 ANK3_HUMAN (120-561): 2.39e-41: 170: 15.54		SKT_HUMAN (4-1091): 0: 1138: 37.96