HitPredict

Interactor 1: YTHD1 (Q9BYJ9)
YTH domain-containing family protein 1 (DF1) (Dermatomyositis associated with cancer putative autoantigen 1) (DACA-1)
Gene: YTHDF1

Interactor 2: AGO2 (Q9UKV8)
Protein argonaute-2 (Argonaute2) (hAgo2) (EC 3.1.26.n2) (Argonaute RISC catalytic component 2) (Eukaryotic translation initiation factor 2C 2) (eIF-2C 2) (eIF2C 2) (PAZ Piwi domain protein) (PPD) (Protein slicer)
Gene: AGO2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	29395067, 24778252
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000932 - P-body GO:0003723 - RNA binding GO:0005737 - cytoplasm GO:0045727 - positive regulation of translation
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 559 Hs			1 859
+	Mm
		1208649 YTHD2_MOUSE (1-558): 1.01e-137: 413: 62.72		AGO2_MOUSE (1-859): 0: 1219: 99.19
+	Hs
		1356635 YTHD2_HUMAN (1-558): 1.49e-138: 415: 62.72		AGO2_HUMAN (1-859): 0: 1205: 100.00
+	Hs
		1317045 YTHD1_HUMAN (1-559): 2.02e-141: 422: 100.00		AGO1_HUMAN (17-859): 0: 1182: 83.16
+	Hs
		1192403 YTHD3_HUMAN (1-541): 4.01e-131: 396: 65.91		AGO2_HUMAN (1-859): 0: 1205: 100.00
+	Hs
		1356725 YTHD2_HUMAN (1-558): 1.49e-138: 415: 62.72		AGO1_HUMAN (17-859): 0: 1182: 83.16
+	Hs
		1317021 YTHD1_HUMAN (1-559): 2.02e-141: 422: 100.00		AGO3_HUMAN (5-859): 0: 1165: 79.75
+	Hs
		1334299 YTHD2_HUMAN (1-558): 1.49e-138: 415: 62.72		AGO3_HUMAN (5-859): 0: 1165: 79.75
+	Hs
		1192405 YTHD3_HUMAN (1-541): 4.01e-131: 396: 65.91		AGO1_HUMAN (17-859): 0: 1182: 83.16
+	Hs
		1192379 YTHD3_HUMAN (1-541): 4.01e-131: 396: 65.91		AGO3_HUMAN (5-859): 0: 1165: 79.75