HitPredict

Interactor 1: HOIL1 (Q9BYM8)
RanBP-type and C3HC4-type zinc finger-containing protein 1 (EC 2.3.2.31) (HBV-associated factor 4) (Heme-oxidized IRP2 ubiquitin ligase 1) (HOIL-1) (Hepatitis B virus X-associated protein 4) (RING finger protein 54) (RING-type E3 ubiquitin transferase HOIL-1) (Ubiquitin-conjugating enzyme 7-interacting protein 3)
Gene: RBCK1

Interactor 2: ZRAN1 (Q9UGI0)
Ubiquitin thioesterase ZRANB1 (EC 3.4.19.12) (TRAF-binding domain-containing protein) (hTrabid) (Zinc finger Ran-binding domain-containing protein 1)
Gene: ZRANB1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	33853758
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0046872 - metal ion binding
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 510 Hs			1 708
+	Hs
		1219385 CUL9_HUMAN (144-496): 3.24e-71: 248: 16.94		ZRAN1_HUMAN (1-697): 0: 987: 100.00
+	Hs
		1354994 ARI1_HUMAN (216-496): 1.87e-68: 231: 18.09		ZRAN1_HUMAN (1-697): 0: 987: 100.00
+	Hs
		312675 ARI2_HUMAN (243-496): 7.23e-65: 220: 19.85		ZRAN1_HUMAN (1-697): 0: 987: 100.00
+	Hs
		599724 HOIL1_HUMAN (1-510): 0: 577: 100.00		TNAP3_HUMAN (392-651): 2.48e-93: 308: 35.74
+	Mm
		1266176 HOIL1_MOUSE (1-510): 0: 562: 91.18		RNF31_MOUSE (8-410): 2.07e-87: 298: 14.99
+	Hs
		1290049 HOIL1_HUMAN (1-510): 0: 577: 100.00		RNF31_HUMAN (29-410): 7.77e-78: 271: 15.73
+	Hs
		275509 HOIL1_HUMAN (1-510): 0: 577: 100.00		CAN15_HUMAN (76-256): 3.1e-11: 69.2: 18.85
+	Hs
		227767 PRKN_HUMAN (210-489): 2.2e-53: 188: 19.80		OTU7B_HUMAN (322-701): 2.32e-127: 400: 25.54
+	Hs
		599730 SHRPN_HUMAN (7-232): 2.94e-75: 244: 39.66		TNAP3_HUMAN (392-651): 2.48e-93: 308: 35.74
+	Mm
		1265107 SHRPN_MOUSE (7-232): 1.12e-74: 242: 38.53		RNF31_MOUSE (8-410): 2.07e-87: 298: 14.99
+	Hs
		599754 ARI1_HUMAN (216-496): 1.87e-68: 231: 18.09		TNAP3_HUMAN (392-651): 2.48e-93: 308: 35.74
+	Hs
		599742 RNF14_HUMAN (242-478): 1.26e-68: 229: 18.99		TNAP3_HUMAN (392-651): 2.48e-93: 308: 35.74
+	Hs
		1290057 SHRPN_HUMAN (7-232): 2.94e-75: 244: 39.66		RNF31_HUMAN (29-410): 7.77e-78: 271: 15.73
+	Hs
		599739 RN216_HUMAN (235-497): 5.21e-52: 191: 19.13		TNAP3_HUMAN (392-651): 2.48e-93: 308: 35.74
+	Hs
		228331 PRKN_HUMAN (210-489): 2.2e-53: 188: 19.80		RNF31_HUMAN (29-410): 7.77e-78: 271: 15.73
+	Hs
		834626 CUL9_HUMAN (144-496): 3.24e-71: 248: 16.94		NU153_HUMAN (109-348): 5.07e-09: 61.9: 11.11
+	Hs
		226864 PRKN_HUMAN (210-489): 2.2e-53: 188: 19.80		RBP2_HUMAN (35-380): 3.46e-21: 101: 9.86
+	Hs
		275510 RN216_HUMAN (235-497): 5.21e-52: 191: 19.13		CAN15_HUMAN (76-256): 3.1e-11: 69.2: 18.85