HitPredict

Interactor 1: KRA41 (Q9BYQ7)
Keratin-associated protein 4-1 (Keratin-associated protein 4-10) (Keratin-associated protein 4.1) (Keratin-associated protein 4.10) (Ultrahigh sulfur keratin-associated protein 4.10)
Gene: KRTAP4-1

Interactor 2: NECT3 (Q9NQS3)
Nectin-3 (CDw113) (Nectin cell adhesion molecule 3) (Poliovirus receptor-related protein 3) (CD antigen CD113)
Gene: NECTIN3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.50	0.553

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, validated two hybrid, two hybrid array, two hybrid prey pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 146 Hs			1 549
+	Hs
		1317297 KR411_HUMAN (3-132): 3.74e-28: 104: 43.14		NECT3_HUMAN (49-549): 5.39e-105: 327: 100.00
+	Hs
		991677 KRA11_HUMAN (2-145): 1.73e-25: 97: 36.42		NECT3_HUMAN (49-549): 5.39e-105: 327: 100.00
+	Hs
		1216397 KRA13_HUMAN (2-146): 2.18e-21: 86.2: 37.91		NECT3_HUMAN (49-549): 5.39e-105: 327: 100.00
+	Hs
		889696 KR108_HUMAN (11-146): 4.83e-20: 84.7: 35.33		NECT3_HUMAN (49-549): 5.39e-105: 327: 100.00
+	Hs
		889902 KR109_HUMAN (3-127): 1.22e-17: 78.9: 31.82		NECT3_HUMAN (49-549): 5.39e-105: 327: 100.00
+	Hs
		889008 KR103_HUMAN (40-146): 4.88e-18: 78.5: 35.19		NECT3_HUMAN (49-549): 5.39e-105: 327: 100.00
+	Hs
		1317255 KRA93_HUMAN (45-146): 2.77e-18: 77.8: 41.18		NECT3_HUMAN (49-549): 5.39e-105: 327: 100.00
+	Hs
		1317337 KRA42_HUMAN (41-146): 5.6e-13: 63.5: 55.96		NECT3_HUMAN (49-549): 5.39e-105: 327: 100.00
+	Hs
		887405 KR122_HUMAN (1-139): 3.69e-26: 97.8: 32.86		NECT2_HUMAN (25-360): 1.8e-62: 215: 28.81
+	Hs
		991636 KRA11_HUMAN (2-145): 1.73e-25: 97: 36.42		NECT2_HUMAN (25-360): 1.8e-62: 215: 28.81
+	Hs
		1216364 KRA13_HUMAN (2-146): 2.18e-21: 86.2: 37.91		NECT2_HUMAN (25-360): 1.8e-62: 215: 28.81
+	Hs
		889610 KR108_HUMAN (11-146): 4.83e-20: 84.7: 35.33		NECT2_HUMAN (25-360): 1.8e-62: 215: 28.81
+	Hs
		888950 KR103_HUMAN (40-146): 4.88e-18: 78.5: 35.19		NECT2_HUMAN (25-360): 1.8e-62: 215: 28.81
+	Hs
		888753 KR101_HUMAN (3-146): 1.58e-15: 72.8: 31.37		NECT2_HUMAN (25-360): 1.8e-62: 215: 28.81
+	Hs
		545103 KRA11_HUMAN (2-145): 1.73e-25: 97: 36.42		PVR_HUMAN (2-269): 4.78e-10: 63.8: 13.33
+	Hs
		545136 KRA13_HUMAN (2-146): 2.18e-21: 86.2: 37.91		PVR_HUMAN (2-269): 4.78e-10: 63.8: 13.33
+	Hs
		545093 KR108_HUMAN (11-146): 4.83e-20: 84.7: 35.33		PVR_HUMAN (2-269): 4.78e-10: 63.8: 13.33
+	Hs
		545094 KR109_HUMAN (3-127): 1.22e-17: 78.9: 31.82		PVR_HUMAN (2-269): 4.78e-10: 63.8: 13.33
+	Hs
		545091 KR103_HUMAN (40-146): 4.88e-18: 78.5: 35.19		PVR_HUMAN (2-269): 4.78e-10: 63.8: 13.33
+	Hs
		545163 KRA93_HUMAN (45-146): 2.77e-18: 77.8: 41.18		PVR_HUMAN (2-269): 4.78e-10: 63.8: 13.33