HitPredict

Interactor 1: TRI55 (Q9BYV6)
Tripartite motif-containing protein 55 (EC 2.3.2.27) (Muscle-specific RING finger protein 2) (MuRF-2) (MuRF2) (RING finger protein 29)
Gene: TRIM55

Interactor 2: PIAS3 (Q9Y6X2)
E3 SUMO-protein ligase PIAS3 (EC 2.3.2.-) (E3 SUMO-protein transferase PIAS3) (Protein inhibitor of activated STAT protein 3)
Gene: PIAS3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	18157088
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0008270 - zinc ion binding
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 548 Hs			1 628
+	Hs
		1282085 TRI63_HUMAN (8-329): 1.6e-80: 257: 61.30		PIAS3_HUMAN (1-628): 0: 879: 100.00
+	Hs
		1318360 TRIM8_HUMAN (18-465): 8.09e-65: 222: 18.25		PIAS3_HUMAN (1-628): 0: 879: 100.00
+	Hs
		537154 TRI27_HUMAN (12-434): 9.25e-65: 221: 14.51		PIAS3_HUMAN (1-628): 0: 879: 100.00
+	Hs
		278161 TRI55_HUMAN (1-548): 6.44e-121: 368: 100.00		PIAS1_HUMAN (1-628): 0: 728: 56.69
+	Hs
		278333 TRI55_HUMAN (1-548): 6.44e-121: 368: 100.00		PIAS2_HUMAN (1-550): 0: 651: 59.00
+	Hs
		278144 TRI63_HUMAN (8-329): 1.6e-80: 257: 61.30		PIAS1_HUMAN (1-628): 0: 728: 56.69
+	Hs
		278162 TRIM5_HUMAN (13-396): 3.08e-68: 230: 14.32		PIAS1_HUMAN (1-628): 0: 728: 56.69
+	Hs
		277914 TRI27_HUMAN (12-434): 9.25e-65: 221: 14.51		PIAS1_HUMAN (1-628): 0: 728: 56.69
+	Hs
		278315 TRI63_HUMAN (8-329): 1.6e-80: 257: 61.30		PIAS2_HUMAN (1-550): 0: 651: 59.00
+	Hs
		278217 TRI27_HUMAN (12-434): 9.25e-65: 221: 14.51		PIAS2_HUMAN (1-550): 0: 651: 59.00
+	Hs
		536921 TRI27_HUMAN (12-434): 9.25e-65: 221: 14.51		PIAS4_HUMAN (2-477): 2.11e-177: 514: 46.71
+	Hs
		278295 TRI67_HUMAN (122-326): 8.33e-14: 76.3: 24.39		PIAS2_HUMAN (1-550): 0: 651: 59.00
+	Hs
		1030009 TIF1B_HUMAN (18-534): 7.29e-67: 233: 15.37		ZMIZ1_HUMAN (79-422): 1.82e-84: 287: 24.93
+	Hs
		1172236 TRI67_HUMAN (122-326): 8.33e-14: 76.3: 24.39		ZMIZ1_HUMAN (79-422): 1.82e-84: 287: 24.93
+	Hs
		1170889 TRI67_HUMAN (122-326): 8.33e-14: 76.3: 24.39		ZMIZ2_HUMAN (81-619): 2.53e-79: 271: 20.46