HitPredict

Interactor 1: BACH2 (Q9BYV9)
Transcription regulator protein BACH2 (BTB and CNC homolog 2)
Gene: BACH2

Interactor 2: NCOR2 (Q9Y618)
Nuclear receptor corepressor 2 (N-CoR2) (CTG repeat protein 26) (SMAP270) (Silencing mediator of retinoic acid and thyroid hormone receptor) (SMRT) (T3 receptor-associating factor) (TRAC) (Thyroid-, retinoic-acid-receptor-associated corepressor)
Gene: NCOR2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 841 Hs			1 2514
+	Hs
		1081269 NF2L2_HUMAN (403-737): 2.87e-68: 239: 20.11		NCOR2_HUMAN (1-2514): 0: 908: 100.00
+	Hs
		312107 ZBT7A_HUMAN (9-508): 2.82e-66: 233: 14.13		NCOR2_HUMAN (1-2514): 0: 908: 100.00
+	Hs
		781496 BCL6_HUMAN (152-580): 2.46e-17: 88.7: 10.41		NCOR2_HUMAN (1-2514): 0: 908: 100.00
+	Hs
		261583 BACH2_HUMAN (1-841): 9.19e-138: 431: 100.00		NCOR1_HUMAN (1-2514): 9.88e-128: 453: 34.38
+	Hs
		157162 BACH1_HUMAN (1-834): 3.72e-128: 403: 31.27		NCOR1_HUMAN (1-2514): 9.88e-128: 453: 34.38
+	Mm
		956178 BACH1_MOUSE (1-834): 6.09e-109: 352: 29.81		NCOR1_MOUSE (1-2514): 8.41e-128: 453: 34.08
+	Hs
		261522 NF2L2_HUMAN (403-737): 2.87e-68: 239: 20.11		NCOR1_HUMAN (1-2514): 9.88e-128: 453: 34.38
+	Hs
		261361 ZBT7A_HUMAN (9-508): 2.82e-66: 233: 14.13		NCOR1_HUMAN (1-2514): 9.88e-128: 453: 34.38
+	Xl
		1246704 KAISO_XENLA (6-645): 3.32e-54: 202: 13.61		NCOR1_XENLA (1-2514): 7.28e-122: 434: 32.87
+	Hs
		261426 BCL6_HUMAN (152-580): 2.46e-17: 88.7: 10.41		NCOR1_HUMAN (1-2514): 9.88e-128: 453: 34.38
+	Hs
		196656 ZBT24_HUMAN (1-754): 6.08e-99: 325: 14.80		CIC_HUMAN (7-2131): 8.47e-18: 93.5: 9.33
+	Hs
		1304783 ZBT18_HUMAN (15-285): 1.92e-49: 184: 26.48		TARA_HUMAN (40-1577): 3.75e-52: 206: 9.68
+	Hs
		312085 ZBT7A_HUMAN (9-508): 2.82e-66: 233: 14.13		CIC_HUMAN (7-2131): 8.47e-18: 93.5: 9.33
+	Hs
		1304807 ZBT18_HUMAN (15-285): 1.92e-49: 184: 26.48		PRC2C_HUMAN (1-1819): 3.07e-18: 94.7: 7.02
+	Hs
		1300910 ZBT18_HUMAN (15-285): 1.92e-49: 184: 26.48		CIC_HUMAN (7-2131): 8.47e-18: 93.5: 9.33
+	Hs
		317637 ZBT11_HUMAN (122-629): 3.97e-19: 95.2: 8.81		RCOR1_HUMAN (388-705): 2.51e-45: 174: 22.05
+	Hs
		1300976 ZN629_HUMAN (119-593): 2.51e-35: 146: 6.48		CIC_HUMAN (7-2131): 8.47e-18: 93.5: 9.33
+	Hs
		1024298 ZBT17_HUMAN (118-516): 1.94e-24: 111: 8.15		CIC_HUMAN (7-2131): 8.47e-18: 93.5: 9.33
+	Hs
		781425 BCL6_HUMAN (152-580): 2.46e-17: 88.7: 10.41		MINT_HUMAN (80-1321): 6.8e-20: 100: 8.11
+	Hs
		781498 BCL6_HUMAN (152-580): 2.46e-17: 88.7: 10.41		CABIN_HUMAN (722-1134): 2.25e-13: 78.9: 19.17