Interactor 1: IFIH1 (Q9BYX4)
Interferon-induced helicase C domain-containing protein 1 (EC 3.6.4.13) (Clinically amyopathic dermatomyositis autoantigen 140 kDa) (CADM-140 autoantigen) (Helicase with 2 CARD domains) (Helicard) (Interferon-induced with helicase C domain protein 1) (Melanoma differentiation-associated protein 5) (MDA-5) (Murabutide down-regulated protein) (RIG-I-like receptor 2) (RLR-2) (RNA helicase-DEAD box protein 116)
Gene: IFIH1
Interactor 2: IFIH1 (Q9BYX4)
Interferon-induced helicase C domain-containing protein 1 (EC 3.6.4.13) (Clinically amyopathic dermatomyositis autoantigen 140 kDa) (CADM-140 autoantigen) (Helicase with 2 CARD domains) (Helicard) (Interferon-induced with helicase C domain protein 1) (Melanoma differentiation-associated protein 5) (MDA-5) (Murabutide down-regulated protein) (RIG-I-like receptor 2) (RLR-2) (RNA helicase-DEAD box protein 116)
Gene: IFIH1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.84 | 1.00 | 0.917 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 28031478, 33727702, 32612200, 25865883, 22160685 |
| Identification Methods | affinity chromatography technology, comigration in non denaturing gel electrophoresis, transmission electron microscopy, molecular sieving, light scattering, electrophoretic mobility shift assay |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | CARD_2~CARD_2, CARD_2~ResIII, CARD_2~RIG-I_C, Helicase_C~Helicase_C, Helicase_C~ResIII, Helicase_C~RIG-I_C, Helicase_C~RIG-I_C-RD, ResIII~ResIII, RIG-I_C~ResIII, RIG-I_C-RD~ResIII, RIG-I_C~RIG-I_C, RIG-I_C~RIG-I_C-RD, RIG-I_C-RD~RIG-I_C-RD |
| Common GO terms | GO:0002753 - cytoplasmic pattern recognition receptor signaling pathway GO:0003677 - DNA binding GO:0003723 - RNA binding GO:0003724 - RNA helicase activity GO:0003725 - double-stranded RNA binding and 28 others more... |
| Homologous interactions | 17 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
