HitPredict

Interactor 1: CPEB1 (Q9BZB8)
Cytoplasmic polyadenylation element-binding protein 1 (CPE-BP1) (CPE-binding protein 1) (h-CPEB) (hCPEB-1)
Gene: CPEB1

Interactor 2: IF2B2 (Q9Y6M1)
Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2 mRNA-binding protein 2) (IMP-2) (Hepatocellular carcinoma autoantigen p62) (IGF-II mRNA-binding protein 2) (VICKZ family member 2)
Gene: IGF2BP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000932 - P-body GO:0003730 - mRNA 3'-UTR binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 566 Hs			1 599
+	Hs
		128293 CPEB1_HUMAN (1-566): 0: 675: 100.00		IF2B3_HUMAN (2-599): 4.89e-134: 405: 62.36
+	Hs
		1317750 CPEB1_HUMAN (1-566): 0: 675: 100.00		IF2B1_HUMAN (2-599): 2.29e-130: 395: 63.89
+	Hs
		1294243 CPEB1_HUMAN (1-566): 0: 675: 100.00		FUBP3_HUMAN (196-414): 3.06e-18: 90.2: 15.51
+	Hs
		1089597 CPEB4_HUMAN (262-563): 3.11e-64: 225: 37.86		IF2B2_HUMAN (1-599): 1.06e-146: 438: 100.00
+	Hs
		1089576 CPEB4_HUMAN (262-563): 3.11e-64: 225: 37.86		IF2B1_HUMAN (2-599): 2.29e-130: 395: 63.89
+	Hs
		852215 ROA3_HUMAN (396-513): 5.3e-20: 94.1: 13.45		IF2B2_HUMAN (1-599): 1.06e-146: 438: 100.00
+	Hs
		128079 ROA3_HUMAN (396-513): 5.3e-20: 94.1: 13.45		IF2B3_HUMAN (2-599): 4.89e-134: 405: 62.36
+	Hs
		852190 ROA3_HUMAN (396-513): 5.3e-20: 94.1: 13.45		IF2B1_HUMAN (2-599): 2.29e-130: 395: 63.89
+	Hs
		1288222 MSI2H_HUMAN (270-432): 6.69e-18: 86.8: 14.63		IF2B1_HUMAN (2-599): 2.29e-130: 395: 63.89
+	Dm
		112950 ORB2_DROME (232-563): 1.43e-62: 220: 34.22		M9NF14_DROME (4-503): 5.85e-23: 105: 14.89
+	Hs
		1089549 CPEB4_HUMAN (262-563): 3.11e-64: 225: 37.86		FUBP3_HUMAN (196-414): 3.06e-18: 90.2: 15.51
+	Hs
		959447 CPEB4_HUMAN (262-563): 3.11e-64: 225: 37.86		VIGLN_HUMAN (444-585): 4.33e-12: 71.5: 19.01
+	Mm
		904318 ROAA_MOUSE (241-518): 1.76e-52: 182: 15.30		HNRPK_MOUSE (386-596): 5.84e-18: 88.9: 17.09
+	Hs
		201664 MSI1H_HUMAN (294-523): 1.03e-55: 193: 21.65		VIGLN_HUMAN (444-585): 4.33e-12: 71.5: 19.01
+	Dm
		112938 RB27C_DROME (312-507): 3.64e-19: 92.1: 19.90		M9NF14_DROME (4-503): 5.85e-23: 105: 14.89
+	Mm
		904286 ROA3_MOUSE (396-513): 5.36e-20: 94.1: 13.45		HNRPK_MOUSE (386-596): 5.84e-18: 88.9: 17.09
+	Hs
		1290128 DAZP1_HUMAN (423-522): 1.21e-17: 87.2: 19.80		FUBP3_HUMAN (196-414): 3.06e-18: 90.2: 15.51
+	Mm
		904354 DAZP1_MOUSE (423-522): 2.29e-17: 86.4: 20.79		HNRPK_MOUSE (386-596): 5.84e-18: 88.9: 17.09
+	Hs
		852064 ROA3_HUMAN (396-513): 5.3e-20: 94.1: 13.45		PCBP1_HUMAN (422-530): 8.21e-11: 65.8: 25.69
+	Hs
		959594 DAZP1_HUMAN (423-522): 1.21e-17: 87.2: 19.80		VIGLN_HUMAN (444-585): 4.33e-12: 71.5: 19.01