HitPredict

Interactor 1: OSBL8 (Q9BZF1)
Oxysterol-binding protein-related protein 8 (ORP-8) (OSBP-related protein 8)
Gene: OSBPL8

Interactor 2: RHOF (Q9HBH0)
Rho-related GTP-binding protein RhoF (Rho family GTPase Rif) (Rho in filopodia)
Gene: RHOF

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~Ras
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 889 Hs			1 211
+	Hs
		120622 OSBL8_HUMAN (1-889): 0: 1210: 100.00		RHOD_HUMAN (5-198): 4.14e-90: 265: 52.06
+	Hs
		925589 OSBL8_HUMAN (1-889): 0: 1210: 100.00		RAC1_HUMAN (20-211): 9.06e-84: 248: 49.48
+	Hs
		545597 OSBL8_HUMAN (1-889): 0: 1210: 100.00		RAC2_HUMAN (20-211): 2.82e-79: 237: 49.48
+	Hs
		951303 OSBL8_HUMAN (1-889): 0: 1210: 100.00		RHOG_HUMAN (19-211): 4.47e-79: 236: 46.11
+	Hs
		900866 OSBL8_HUMAN (1-889): 0: 1210: 100.00		RHOA_HUMAN (21-211): 1.51e-78: 235: 48.69
+	Hs
		564672 OSBL8_HUMAN (1-889): 0: 1210: 100.00		RHOQ_HUMAN (14-209): 4.28e-77: 232: 46.43
+	Hs
		892574 OSBL8_HUMAN (1-889): 0: 1210: 100.00		RAC3_HUMAN (20-193): 1.33e-77: 232: 50.58
+	Hs
		894394 OSBL8_HUMAN (1-889): 0: 1210: 100.00		CDC42_HUMAN (19-211): 1.19e-77: 232: 44.04
+	Hs
		436490 OSBL8_HUMAN (1-889): 0: 1210: 100.00		RHOC_HUMAN (21-211): 1.44e-76: 230: 49.22
+	Hs
		915944 OSBL8_HUMAN (1-889): 0: 1210: 100.00		RHOB_HUMAN (21-200): 2.02e-58: 184: 48.89
+	Hs
		120600 OSBL9_HUMAN (209-743): 5.35e-159: 484: 30.32		RHOD_HUMAN (5-198): 4.14e-90: 265: 52.06
+	Hs
		545575 OSBL9_HUMAN (209-743): 5.35e-159: 484: 30.32		RAC2_HUMAN (20-211): 2.82e-79: 237: 49.48
+	Hs
		564655 OSBL9_HUMAN (209-743): 5.35e-159: 484: 30.32		RHOQ_HUMAN (14-209): 4.28e-77: 232: 46.43
+	Hs
		925615 OSBL3_HUMAN (250-757): 1.65e-143: 449: 18.81		RAC1_HUMAN (20-211): 9.06e-84: 248: 49.48
+	Hs
		545617 OSBL3_HUMAN (250-757): 1.65e-143: 449: 18.81		RAC2_HUMAN (20-211): 2.82e-79: 237: 49.48
+	Hs
		900901 OSBL3_HUMAN (250-757): 1.65e-143: 449: 18.81		RHOA_HUMAN (21-211): 1.51e-78: 235: 48.69
+	Hs
		892595 OSBL3_HUMAN (250-757): 1.65e-143: 449: 18.81		RAC3_HUMAN (20-193): 1.33e-77: 232: 50.58
+	Hs
		436507 OSBL3_HUMAN (250-757): 1.65e-143: 449: 18.81		RHOC_HUMAN (21-211): 1.44e-76: 230: 49.22
+	Hs
		915945 OSBL6_HUMAN (250-756): 1.6e-143: 450: 20.96		RHOB_HUMAN (21-200): 2.02e-58: 184: 48.89
+	Hs
		915974 OSBL3_HUMAN (250-757): 1.65e-143: 449: 18.81		RHOB_HUMAN (21-200): 2.02e-58: 184: 48.89