Interactor 1: REN3B (Q9BZI7)
Regulator of nonsense transcripts 3B (Nonsense mRNA reducing factor 3B) (Up-frameshift suppressor 3 homolog B) (hUpf3B) (Up-frameshift suppressor 3 homolog on chromosome X) (hUpf3p-X)
Gene: UPF3B

Interactor 2: RENT2 (Q9HAU5)
Regulator of nonsense transcripts 2 (Up-frameshift suppressor 2 homolog) (hUpf2)
Gene: UPF2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.980

The method score is based on:

Property Details
Experiments 26496610, 15231747, 12417715, 11163187, 14527413, 16452507, 22522823, 20479275, 18066079, 19503078, 16601204, 12718880
Identification Methods affinity chromatography technology, two hybrid, molecular sieving, surface plasmon resonance, transmission electron microscopy, pull down, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains MIF4G~Smg4_UPF3
Common GO terms GO:0000184 - nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 1 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 483
Hs

1 1272
+ Hs
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024