HitPredict

Interactor 1: TBL1R (Q9BZK7)
F-box-like/WD repeat-containing protein TBL1XR1 (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1) (TBL1-related protein 1) (Transducin beta-like 1X-related protein 1)
Gene: TBL1XR1

Interactor 2: PKHA4 (Q9H4M7)
Pleckstrin homology domain-containing family A member 4 (PH domain-containing family A member 4) (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1)
Gene: PLEKHA4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31091453
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~WD40
Common GO terms	GO:0090263 - positive regulation of canonical Wnt signaling pathway
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 514 Hs			1 779
+	Hs
		793030 LIS1_HUMAN (4-430): 6.86e-96: 298: 17.26		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		1309164 TBL1Y_HUMAN (246-514): 5.05e-59: 205: 20.68		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		1016326 TBL3_HUMAN (131-514): 2.98e-55: 200: 15.00		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		903516 WDR5_HUMAN (17-334): 1.51e-56: 193: 14.46		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		1153371 TBL1R_HUMAN (1-514): 1.37e-162: 472: 100.00		PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02
+	Hs
		1331436 NLE1_HUMAN (23-293): 5.57e-36: 141: 13.61		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		283021 CIAO1_HUMAN (169-472): 3.95e-22: 99.4: 27.94		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		1288303 SNR40_HUMAN (50-195): 7.63e-12: 68.7: 11.92		PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00
+	Hs
		1153322 FBXW7_HUMAN (39-423): 4.25e-69: 236: 15.64		PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02
+	Hs
		1167395 FBXW7_HUMAN (39-423): 4.25e-69: 236: 15.64		MPRIP_HUMAN (2-499): 4.76e-44: 173: 16.57
+	Hs
		1148943 FBXW7_HUMAN (39-423): 4.25e-69: 236: 15.64		CYTSA_HUMAN (320-643): 3.92e-43: 171: 12.81
+	Hs
		903302 WDR5_HUMAN (17-334): 1.51e-56: 193: 14.46		PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02
+	Hs
		1016298 TBL3_HUMAN (131-514): 2.98e-55: 200: 15.00		RHG24_HUMAN (55-181): 6.43e-27: 119: 25.93
+	Hs
		787153 TBL3_HUMAN (131-514): 2.98e-55: 200: 15.00		RHG25_HUMAN (30-181): 1.01e-21: 102: 23.27
+	Hs
		282925 CIAO1_HUMAN (169-472): 3.95e-22: 99.4: 27.94		PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02
+	Hs
		1240465 POC1A_HUMAN (49-259): 2.12e-27: 115: 10.46		PKHA5_HUMAN (2-653): 1.62e-36: 150: 17.61
+	Hs
		283033 CIAO1_HUMAN (169-472): 3.95e-22: 99.4: 27.94		PKHA5_HUMAN (2-653): 1.62e-36: 150: 17.61
+	Hs
		283034 CIAO1_HUMAN (169-472): 3.95e-22: 99.4: 27.94		PKHA2_HUMAN (1-258): 2.68e-38: 149: 15.90