HitPredict - High confidence protein-protein interactions

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	30652415
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	C1_1~C1_1, C1_1~PH, C1_1~Pkinase, PH~PH, PH~Pkinase, Pkinase~Pkinase
Common GO terms	GO:0001525 - angiogenesis GO:0001938 - positive regulation of endothelial cell proliferation GO:0002250 - adaptive immune response GO:0004672 - protein kinase activity GO:0004674 - protein serine/threonine kinase activity and 39 others more... GO:0004697 - diacylglycerol-dependent serine/threonine kinase activity GO:0005080 - protein kinase C binding GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005794 - Golgi apparatus GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0006468 - protein phosphorylation GO:0007155 - cell adhesion GO:0007200 - phospholipase C-activating G protein-coupled receptor signaling pathway GO:0010595 - positive regulation of endothelial cell migration GO:0018105 - peptidyl-serine phosphorylation GO:0018107 - peptidyl-threonine phosphorylation GO:0030148 - sphingolipid biosynthetic process GO:0030949 - positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0032743 - positive regulation of interleukin-2 production GO:0032757 - positive regulation of interleukin-8 production GO:0035556 - intracellular signal transduction GO:0035924 - cellular response to vascular endothelial growth factor stimulus GO:0043536 - positive regulation of blood vessel endothelial cell migration GO:0045743 - positive regulation of fibroblast growth factor receptor signaling pathway GO:0045766 - positive regulation of angiogenesis GO:0045785 - positive regulation of cell adhesion GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0046777 - protein autophosphorylation GO:0046872 - metal ion binding GO:0048010 - vascular endothelial growth factor receptor signaling pathway GO:0050852 - T cell receptor signaling pathway GO:0050862 - positive regulation of T cell receptor signaling pathway GO:0051091 - positive regulation of DNA-binding transcription factor activity GO:0051092 - positive regulation of NF-kappaB transcription factor activity GO:0061154 - endothelial tube morphogenesis GO:0070232 - regulation of T cell apoptotic process GO:0070374 - positive regulation of ERK1 and ERK2 cascade GO:0106310 - protein serine kinase activity GO:2000573 - positive regulation of DNA biosynthetic process GO:2001028 - positive regulation of endothelial cell chemotaxis
Homologous interactions	16