HitPredict

Interactor 1: EDEM3 (Q9BZQ6)
ER degradation-enhancing alpha-mannosidase-like protein 3 (EC 3.2.1.113) (Alpha-1,2-mannosidase EDEM3)
Gene: EDEM3

Interactor 2: HYOU1 (Q9Y4L1)
Hypoxia up-regulated protein 1 (150 kDa oxygen-regulated protein) (ORP-150) (170 kDa glucose-regulated protein) (GRP-170) (Heat shock protein family H member 4)
Gene: HYOU1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	28366632
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0005788 - endoplasmic reticulum lumen GO:0016020 - membrane
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 932 Hs			1 999
+	Hs
		1267744 EDEM3_HUMAN (1-932): 0: 1458: 100.00		HS105_HUMAN (33-960): 0: 812: 24.46
+	Hs
		320907 EDEM3_HUMAN (1-932): 0: 1458: 100.00		HS74L_HUMAN (33-960): 0: 793: 24.57
+	Hs
		714066 EDEM3_HUMAN (1-932): 0: 1458: 100.00		HS71L_HUMAN (682-814): 9.92e-31: 131: 15.04
+	Hs
		504710 EDEM3_HUMAN (1-932): 0: 1458: 100.00		HSP7C_HUMAN (682-815): 2.07e-30: 130: 16.42
+	Hs
		1268042 EDEM1_HUMAN (43-514): 0: 605: 42.42		HYOU1_HUMAN (1-999): 0: 859: 100.00
+	Hs
		504492 EDEM1_HUMAN (43-514): 0: 605: 42.42		HSP7C_HUMAN (682-815): 2.07e-30: 130: 16.42