HitPredict

Interactor 1: TRIM6 (Q9C030)
Tripartite motif-containing protein 6 (EC 2.3.2.27) (RING finger protein 89) (RING-type E3 ubiquitin transferase TRIM6)
Gene: TRIM6

Interactor 2: TRIM6 (Q9C030)
Tripartite motif-containing protein 6 (EC 2.3.2.27) (RING finger protein 89) (RING-type E3 ubiquitin transferase TRIM6)
Gene: TRIM6

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.77 1.00 0.878

The method score is based on:

Property Details
Experiments 31992359, 11331580, 17156811, 21680743
Identification Methods affinity chromatography technology, two hybrid, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains SPRY~SPRY, zf-B_box~zf-B_box, zf-B_box~zf-RING_UBOX, zf-RING_UBOX~zf-RING_UBOX
Common GO terms GO:0000209 - protein polyubiquitination
GO:0002230 - positive regulation of defense response to virus by host
GO:0002720 - positive regulation of cytokine production involved in immune response
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
and 27 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 488
Hs

1 488
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024