HitPredict

Interactor 1: IN80B (Q9C086)
INO80 complex subunit B (High mobility group AT-hook 1-like 4) (IES2 homolog) (hIes2) (PAP-1-associated protein 1) (PAPA-1) (Zinc finger HIT domain-containing protein 4)
Gene: INO80B

Interactor 2: RUVB1 (Q9Y265)
RuvB-like 1 (EC 3.6.4.12) (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (54 kDa erythrocyte cytosolic protein) (ECP-54) (INO80 complex subunit H) (Nuclear matrix protein 238) (NMP 238) (Pontin 52) (TIP49a) (TIP60-associated protein 54-alpha) (TAP54-alpha)
Gene: RUVBL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.84	1.00	0.919

The method score is based on:

Property	Details
Experiments	28514442, 33961781, 17721549, 28561026, 16230350
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	TIP49~zf-HIT
Common GO terms	GO:0000723 - telomere maintenance GO:0005654 - nucleoplasm GO:0006275 - regulation of DNA replication GO:0006281 - DNA repair GO:0006282 - regulation of DNA repair and 10 others more... GO:0006310 - DNA recombination GO:0006338 - chromatin remodeling GO:0031011 - Ino80 complex GO:0033044 - regulation of chromosome organization GO:0045739 - positive regulation of DNA repair GO:0045893 - positive regulation of DNA-templated transcription GO:0045995 - regulation of embryonic development GO:0051726 - regulation of cell cycle GO:0060382 - regulation of DNA strand elongation GO:1904507 - positive regulation of telomere maintenance in response to DNA damage
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1	356
Hs

1	456

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024