HitPredict

Interactor 1: AMRA1 (Q9C0C7)
Activating molecule in BECN1-regulated autophagy protein 1 (DDB1- and CUL4-associated factor 3)
Gene: AMBRA1

Interactor 2: ASB8 (Q9H765)
Ankyrin repeat and SOCS box protein 8 (ASB-8)
Gene: ASB8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.694

Property	Details
Experiments	26186194, 28514442, 33961781, 24337577
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1298 Hs			1 288
+	Hs
		883639 AMRA1_HUMAN (1-1298): 0: 1603: 100.00		RIPK4_HUMAN (25-287): 2.25e-48: 173: 22.56
+	Hs
		1264019 AMRA1_HUMAN (1-1298): 0: 1603: 100.00		ASB13_HUMAN (13-154): 3.46e-36: 132: 34.97
+	Hs
		1219841 AMRA1_HUMAN (1-1298): 0: 1603: 100.00		ANKH1_HUMAN (2-144): 2.99e-32: 127: 24.00
+	Hs
		276212 AMRA1_HUMAN (1-1298): 0: 1603: 100.00		PSD10_HUMAN (114-255): 1.44e-27: 108: 26.19
+	Hs
		903354 WDR5_HUMAN (3-297): 2.47e-87: 289: 18.39		ANKH1_HUMAN (2-144): 2.99e-32: 127: 24.00
+	Hs
		1288300 SNR40_HUMAN (45-329): 6.16e-55: 197: 11.75		TNKS2_HUMAN (1-101): 1.15e-19: 90.9: 21.57
+	Hs
		166894 LIS1_HUMAN (123-346): 3.66e-35: 141: 11.45		ANR28_HUMAN (14-139): 2.67e-19: 89.8: 21.08
+	Hs
		1219809 FBXW7_HUMAN (164-329): 5.74e-18: 91.8: 9.58		ANKH1_HUMAN (2-144): 2.99e-32: 127: 24.00