HitPredict

Interactor 1: GRIP2 (Q9C0E4)
Glutamate receptor-interacting protein 2 (GRIP-2)
Gene: GRIP2

Interactor 2: GIT1 (Q9Y2X7)
ARF GTPase-activating protein GIT1 (ARF GAP GIT1) (Cool-associated and tyrosine-phosphorylated protein 1) (CAT-1) (CAT1) (G protein-coupled receptor kinase-interactor 1) (GRK-interacting protein 1) (p95-APP1)
Gene: GIT1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	12629171
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1043 Hs			1 761
+	Hs
		1304058 GRIP1_HUMAN (3-1041): 5.23e-174: 541: 56.39		AGAP2_HUMAN (2-223): 3.67e-52: 198: 32.00
+	Rn
		957055 GRIP1_RAT (3-1041): 1.67e-172: 536: 56.76		AGAP2_RAT (2-223): 2.7e-48: 186: 29.28
+	Mm
		1112639 GRIP1_MOUSE (3-1041): 5.62e-170: 530: 56.53		AGAP2_MOUSE (2-223): 9.71e-49: 188: 29.28
+	Mm
		1143335 DLG4_MOUSE (509-808): 1.72e-33: 140: 14.97		GIT1_MOUSE (1-761): 7.5e-170: 509: 96.62
+	Hs
		1020239 PTN13_HUMAN (12-258): 2.73e-23: 109: 18.15		GIT1_HUMAN (1-761): 1.3e-176: 527: 100.00
+	Hs
		1050094 SCRIB_HUMAN (511-740): 6.04e-22: 104: 20.51		GIT1_HUMAN (1-761): 1.3e-176: 527: 100.00
+	Hs
		1049946 SCRIB_HUMAN (511-740): 6.04e-22: 104: 20.51		GIT2_HUMAN (1-758): 2.93e-147: 451: 64.39
+	Mm
		1112634 LNX2_MOUSE (4-230): 1.77e-39: 159: 21.15		AGAP2_MOUSE (2-223): 9.71e-49: 188: 29.28
+	Mm
		1112581 DLG4_MOUSE (509-808): 1.72e-33: 140: 14.97		AGAP2_MOUSE (2-223): 9.71e-49: 188: 29.28
+	Hs
		280069 MPDZ_HUMAN (6-230): 5.76e-32: 137: 20.62		TNKS2_HUMAN (135-556): 6.36e-46: 179: 10.94
+	Mm
		88312 D3YUZ8_MOUSE (3-281): 2.47e-27: 121: 18.69		AGAP2_MOUSE (2-223): 9.71e-49: 188: 29.28
+	Hs
		1021587 DLG1_HUMAN (778-1028): 3.02e-12: 73.1: 14.34		ASAP1_HUMAN (2-606): 1.67e-61: 226: 17.06
+	Hs
		1300695 MAGI1_HUMAN (45-884): 7.63e-16: 85.1: 10.59		AGAP1_HUMAN (2-223): 4.13e-57: 211: 32.89
+	Mm
		1112570 Q52KF7_MOUSE (3-138): 6.69e-23: 107: 25.36		AGAP2_MOUSE (2-223): 9.71e-49: 188: 29.28
+	Mm
		936177 DLG3_MOUSE (3-352): 1.55e-22: 106: 14.41		AGAP2_MOUSE (2-223): 9.71e-49: 188: 29.28
+	Hs
		280009 MPDZ_HUMAN (6-230): 5.76e-32: 137: 20.62		TNKS1_HUMAN (60-480): 1.04e-37: 154: 12.78
+	Mm
		100127 F6UDT8_MOUSE (622-765): 2.73e-16: 83.7: 21.57		AGAP2_MOUSE (2-223): 9.71e-49: 188: 29.28
+	Mm
		1112610 DLG1_MOUSE (790-1028): 1.33e-12: 74.3: 15.45		AGAP2_MOUSE (2-223): 9.71e-49: 188: 29.28
+	Mm
		1112635 DLG2_MOUSE (935-1023): 1.37e-12: 74.2: 26.04		AGAP2_MOUSE (2-223): 9.71e-49: 188: 29.28
+	Mm
		103602 DLG4_MOUSE (509-808): 1.72e-33: 140: 14.97		ANK3_MOUSE (237-740): 1.36e-20: 99.9: 9.25