HitPredict

Interactor 1: BC11B (Q9C0K0)
B-cell lymphoma/leukemia 11B (BCL-11B) (B-cell CLL/lymphoma 11B) (COUP-TF-interacting protein 2) (Radiation-induced tumor suppressor gene 1 protein) (hRit1)
Gene: BCL11B

Interactor 2: BC11A (Q9H165)
B-cell lymphoma/leukemia 11A (BCL-11A) (B-cell CLL/lymphoma 11A) (COUP-TF-interacting protein 1) (Ecotropic viral integration site 9 protein homolog) (EVI-9) (Zinc finger protein 856)
Gene: BCL11A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	24981860, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	zf-C2H2~zf-C2H2
Common GO terms	GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0003700 - DNA-binding transcription factor activity GO:0005634 - nucleus GO:0016514 - SWI/SNF complex GO:0045944 - positive regulation of transcription by RNA polymerase II and 1 others more... GO:0046872 - metal ion binding
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 894 Hs			1 835
+	Hs
		1328473 BC11A_HUMAN (1-889): 1.21e-165: 505: 49.02		BC11A_HUMAN (1-835): 0: 718: 100.00
+	Hs
		1260515 BC11A_HUMAN (1-889): 1.21e-165: 505: 49.02		ZN296_HUMAN (375-451): 3.26e-11: 68.6: 46.84
+	Hs
		997500 ZN616_HUMAN (46-518): 1.87e-146: 453: 13.54		ZSA5A_HUMAN (369-427): 1.8e-18: 91.7: 42.37
+	Hs
		150374 ZN195_HUMAN (425-477): 4.59e-09: 62: 52.83		ZN484_HUMAN (2-322): 2.58e-89: 303: 10.59
+	Hs
		563492 ZNF22_HUMAN (792-848): 5.31e-09: 59.3: 43.86		ZN808_HUMAN (1-371): 1.25e-82: 285: 9.68
+	Hs
		563519 ZNF22_HUMAN (792-848): 5.31e-09: 59.3: 43.86		ZN624_HUMAN (2-195): 1.77e-55: 207: 11.80
+	Hs
		64162 ZN726_HUMAN (378-569): 5.54e-38: 152: 20.10		ZN430_HUMAN (738-818): 3.33e-10: 65.5: 44.44
+	Hs
		64164 ZN726_HUMAN (378-569): 5.54e-38: 152: 20.10		ZN492_HUMAN (738-818): 3.62e-10: 65.5: 41.98
+	Hs
		64156 ZN726_HUMAN (378-569): 5.54e-38: 152: 20.10		ZN716_HUMAN (738-824): 4.35e-09: 61.6: 42.53
+	Hs
		264766 ZN479_HUMAN (792-857): 1.53e-09: 63.5: 46.97		ZN254_HUMAN (716-835): 1.31e-20: 99.1: 22.50
+	Hs
		1260514 BC11B_HUMAN (856-894): 9.88e-10: 64.4: 23.08		ZN296_HUMAN (375-451): 3.26e-11: 68.6: 46.84
+	Hs
		1204925 ZN677_HUMAN (429-477): 5.41e-09: 62: 53.06		ZN430_HUMAN (738-818): 3.33e-10: 65.5: 44.44
+	Hs
		150381 ZN195_HUMAN (425-477): 4.59e-09: 62: 52.83		ZN695_HUMAN (738-820): 1.45e-09: 63.5: 39.76
+	Hs
		1254432 ZN492_HUMAN (425-477): 6.61e-09: 61.6: 52.83		ZN675_HUMAN (738-792): 2.48e-09: 62.8: 52.73
+	Hs
		150380 ZN195_HUMAN (425-477): 4.59e-09: 62: 52.83		ZN677_HUMAN (371-427): 8.76e-09: 60.8: 50.88