HitPredict

Interactor 1: ATX1 (Q9C5X4)
Histone H3-lysine(4) N-trimethyltransferase ATX1 (EC 2.1.1.354) (Protein SET DOMAIN GROUP 27) (Protein-lysine N-trimethyltransferase ATX1-SoloSET) (EC 2.1.1.-) (Trithorax-homolog protein 1) (TRX-homolog protein 1)
Gene: ATX1

Interactor 2: WDR5A (Q9M2Z2)
COMPASS-like H3K4 histone methylase component WDR5A (AtWDR5A)
Gene: WDR5A

Species: Arabidopsis thaliana

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.46	1.00	0.680

Property	Details
Experiments	19567704
Identification Methods	two hybrid, pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	SET~WD40
Common GO terms	GO:0005634 - nucleus GO:0010228 - vegetative to reproductive phase transition of meristem GO:0032259 - methylation GO:0048188 - Set1C/COMPASS complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1062 At			1 317
+	Dm
		1129076 SET1_DROME (799-1038): 1.92e-70: 260: 34.54		WDS_DROME (2-274): 4.48e-84: 259: 28.67
+	Hs
		903149 KMT2A_HUMAN (803-1038): 1.47e-67: 251: 38.08		WDR5_HUMAN (2-274): 2.12e-84: 259: 28.32
+	Hs
		903609 SET1B_HUMAN (797-1038): 2.66e-66: 247: 32.51		WDR5_HUMAN (2-274): 2.12e-84: 259: 28.32
+	Hs
		903374 KMT2C_HUMAN (798-1038): 3.96e-65: 244: 32.52		WDR5_HUMAN (2-274): 2.12e-84: 259: 28.32
+	Mm
		903669 KMT2C_MOUSE (798-1038): 4.73e-65: 244: 32.52		WDR5_MOUSE (2-274): 2.12e-84: 259: 28.32
+	Hs
		165657 SET1A_HUMAN (800-1038): 4.23e-58: 221: 32.22		WDR5_HUMAN (2-274): 2.12e-84: 259: 28.32
+	Hs
		1268048 JADE3_HUMAN (466-873): 6.43e-85: 294: 21.48		SNR40_HUMAN (185-317): 2.54e-32: 124: 23.70
+	Hs
		331862 NSD2_HUMAN (608-1051): 3.61e-77: 279: 18.16		SNR40_HUMAN (185-317): 2.54e-32: 124: 23.70
+	Hs
		975303 KMT2A_HUMAN (803-1038): 1.47e-67: 251: 38.08		FBXW7_HUMAN (140-317): 8.48e-41: 152: 30.17
+	Hs
		152622 KMT2D_HUMAN (813-1038): 3.4e-27: 122: 35.93		WDR5_HUMAN (2-274): 2.12e-84: 259: 28.32
+	Hs
		1080207 EZH2_HUMAN (749-1022): 3.8e-61: 225: 22.94		FBXW7_HUMAN (140-317): 8.48e-41: 152: 30.17
+	Hs
		975304 KMT2A_HUMAN (803-1038): 1.47e-67: 251: 38.08		SNR40_HUMAN (185-317): 2.54e-32: 124: 23.70
+	Hs
		152663 KMT2D_HUMAN (813-1038): 3.4e-27: 122: 35.93		WDR5B_HUMAN (2-270): 1.04e-81: 252: 29.82
+	Hs
		1317584 SETD2_HUMAN (778-1054): 5.55e-62: 234: 18.86		NLE1_HUMAN (181-314): 7.56e-36: 136: 25.00
+	Hs
		876613 AF17_HUMAN (607-848): 9.81e-64: 237: 27.78		SNR40_HUMAN (185-317): 2.54e-32: 124: 23.70
+	Hs
		1288291 SETD2_HUMAN (778-1054): 5.55e-62: 234: 18.86		SNR40_HUMAN (185-317): 2.54e-32: 124: 23.70
+	Sp
		195053 SET1_SCHPO (780-1038): 4.5e-60: 224: 32.69		SWD3_SCHPO (180-312): 2.07e-11: 65.9: 29.32
+	Sc
		744551 SET1_YEAST (871-1038): 9.86e-30: 130: 39.77		SWD3_YEAST (21-312): 6.28e-41: 146: 31.31
+	Hs
		152678 KMT2D_HUMAN (813-1038): 3.4e-27: 122: 35.93		FBXW7_HUMAN (140-317): 8.48e-41: 152: 30.17
+	Hs
		1288292 NSD3_HUMAN (445-886): 1.59e-16: 87.3: 13.03		SNR40_HUMAN (185-317): 2.54e-32: 124: 23.70