HitPredict

Interactor 1: NCHL1 (O00533)
Neural cell adhesion molecule L1-like protein (Close homolog of L1) [Cleaved into: Processed neural cell adhesion molecule L1-like protein]
Gene: CHL1

Interactor 2: LEG1 (P09382)
Galectin-1 (Gal-1) (14 kDa laminin-binding protein) (HLBP14) (14 kDa lectin) (Beta-galactoside-binding lectin L-14-I) (Galaptin) (HBL) (HPL) (Lactose-binding lectin 1) (Lectin galactoside-binding soluble 1) (Putative MAPK-activating protein PM12) (S-Lac lectin 1)
Gene: LGALS1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0070062 - extracellular exosome
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1208 Hs			1 135
+	Hs
		449332 NRCAM_HUMAN (12-1208): 0: 688: 37.15		LEG1_HUMAN (1-135): 2.27e-54: 168: 100.00
+	Hs
		449334 NEO1_HUMAN (5-1018): 1.52e-117: 400: 17.04		LEG1_HUMAN (1-135): 2.27e-54: 168: 100.00
+	Hs
		449205 L1CAM_HUMAN (11-993): 2.57e-90: 320: 16.26		LEG1_HUMAN (1-135): 2.27e-54: 168: 100.00
+	Hs
		449306 SDK1_HUMAN (163-1208): 7.38e-62: 235: 14.66		LEG1_HUMAN (1-135): 2.27e-54: 168: 100.00
+	Hs
		572394 SDK1_HUMAN (163-1208): 7.38e-62: 235: 14.66		LEG3_HUMAN (3-134): 1.88e-49: 160: 28.47
+	Hs
		449281 SDK2_HUMAN (5-1144): 5.07e-54: 210: 13.30		LEG1_HUMAN (1-135): 2.27e-54: 168: 100.00
+	Hs
		814978 SDK1_HUMAN (163-1208): 7.38e-62: 235: 14.66		LEG7_HUMAN (1-132): 1.27e-43: 141: 33.58
+	Hs
		572370 SDK2_HUMAN (5-1144): 5.07e-54: 210: 13.30		LEG3_HUMAN (3-134): 1.88e-49: 160: 28.47
+	Hs
		121183 SDK1_HUMAN (163-1208): 7.38e-62: 235: 14.66		LEG8_HUMAN (12-134): 1.22e-36: 128: 28.13
+	Hs
		814965 SDK2_HUMAN (5-1144): 5.07e-54: 210: 13.30		LEG7_HUMAN (1-132): 1.27e-43: 141: 33.58