HitPredict

Interactor 1: IOS1 (Q9C8I6)
LRR receptor-like serine/threonine-protein kinase IOS1 (EC 2.7.11.-) (Protein IMPAIRED OOMYCETE SUSCEPTIBILITY 1)
Gene: IOS1

Interactor 2: SRF7 (Q9LUL4)
Protein STRUBBELIG-RECEPTOR FAMILY 7 (Leucine-rich repeat receptor kinase-like protein SRF7)
Gene: SRF7

Species: Arabidopsis thaliana

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.58	1.00	0.768

Property	Details
Experiments	29320478, 30806640
Identification Methods	pull down, solid phase assay
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	LRR_1~LRR_8, LRR_8~LRR_8, LRR_8~LRRNT_2, LRR_8~PK_Tyr_Ser-Thr, PK_Tyr_Ser-Thr~Pkinase
Common GO terms	GO:0005524 - ATP binding GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 894 At			1 717
+	At
		1338136 RLK6_ARATH (8-894): 0: 918: 50.67		SRF7_ARATH (1-717): 0: 634: 100.00
+	At
		1320743 IOS1_ARATH (1-894): 0: 937: 100.00		SRF6_ARATH (1-717): 0: 604: 76.52
+	At
		1247258 IOS1_ARATH (1-894): 0: 937: 100.00		SUB_ARATH (9-694): 4.09e-168: 503: 31.68
+	At
		84420 RLK6_ARATH (8-894): 0: 918: 50.67		IMK3_ARATH (2-706): 2.82e-175: 522: 22.31
+	At
		186376 IOS1_ARATH (1-894): 0: 937: 100.00		O22138_ARATH (35-694): 2.03e-165: 494: 25.94
+	At
		3763 IOS1_ARATH (1-894): 0: 937: 100.00		A0A178UFM8_ARATH (26-690): 1.23e-161: 484: 26.76
+	At
		1320744 IOS1_ARATH (1-894): 0: 937: 100.00		Y1668_ARATH (9-694): 8.16e-160: 479: 24.79
+	At
		186384 RLK6_ARATH (8-894): 0: 918: 50.67		O22138_ARATH (35-694): 2.03e-165: 494: 25.94
+	At
		1320752 IOS1_ARATH (1-894): 0: 937: 100.00		Y1680_ARATH (30-715): 1.35e-157: 473: 25.07
+	At
		1323302 RLK6_ARATH (8-894): 0: 918: 50.67		Q9FHM8_ARATH (26-690): 1.23e-161: 484: 26.76
+	At
		3772 RLK6_ARATH (8-894): 0: 918: 50.67		A0A178UFM8_ARATH (26-690): 1.23e-161: 484: 26.76
+	At
		1321336 RLK6_ARATH (8-894): 0: 918: 50.67		Y3868_ARATH (5-717): 6.49e-159: 475: 23.58
+	At
		1114699 IOS1_ARATH (1-894): 0: 937: 100.00		ERECT_ARATH (11-347): 1.62e-61: 224: 19.89
+	At
		85365 IOS1_ARATH (1-894): 0: 937: 100.00		ERL1_ARATH (1-428): 2.42e-60: 220: 17.53
+	At
		249724 IOS1_ARATH (1-894): 0: 937: 100.00		BAME3_ARATH (1-369): 8.25e-58: 214: 18.87
+	At
		1278201 IOS1_ARATH (1-894): 0: 937: 100.00		BAK1_ARATH (1-232): 1.87e-36: 147: 26.16
+	At
		1277303 IOS1_ARATH (1-894): 0: 937: 100.00		SERK1_ARATH (3-182): 1.15e-35: 145: 19.14
+	At
		1320763 IOS1_ARATH (1-894): 0: 937: 100.00		BRL1_ARATH (1-308): 2.93e-31: 133: 23.28
+	At
		1167625 IOS1_ARATH (1-894): 0: 937: 100.00		ERL2_ARATH (143-412): 8.6e-19: 93.5: 9.16
+	At
		1320749 IOS1_ARATH (1-894): 0: 937: 100.00		BRL3_ARATH (69-175): 4.43e-16: 84.6: 19.27