HitPredict

Interactor 1: CPSF3 (Q9C952)
Cleavage and polyadenylation specificity factor subunit 3-I (EC 3.1.27.-) (Cleavage and polyadenylation specificity factor 73 kDa subunit I) (AtCPSF73-I) (CPSF 73 kDa subunit I)
Gene: CPSF73-I

Interactor 2: CPSF2 (Q9LKF9)
Cleavage and polyadenylation specificity factor subunit 2 (Cleavage and polyadenylation specificity factor 100 kDa subunit) (AtCPSF100) (CPSF 100 kDa subunit) (Protein EMBRYO DEFECTIVE 1265) (Protein ENHANCED SILENCING PHENOTYPE 5)
Gene: CPSF100

Species: Arabidopsis thaliana

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.83 1.00 0.912

The method score is based on:

Property Details
Experiments 16897494, 19748916, 18479511, 17008405
Identification Methods pull down, affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Beta-Casp~Beta-Casp, Beta-Casp~Lactamase_B_6, Beta-Casp~RMMBL, CPSF73-100_C~Lactamase_B_6, Lactamase_B_6~Lactamase_B_6, Lactamase_B_6~RMMBL, RMMBL~RMMBL
Common GO terms GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005847 - mRNA cleavage and polyadenylation specificity factor complex
GO:0006398 - mRNA 3'-end processing by stem-loop binding and cleavage
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 693
At

1 739
+ Hs
+ Dm
+ At
+ Zm
+ At
+ At
+ Sp
+ Sp
+ Sc
+ At
+ At
+ Dm
+ Hs
+ Mt
+ Bs
+ Bs

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Last updated: 15 Jul 2024