HitPredict

Interactor 1: CDKD2 (Q9C9M7)
Cyclin-dependent kinase D-2 (CDKD;2) (EC 2.7.11.22) (EC 2.7.11.23) (CDK-activating kinase 4-At) (CAK4-At)
Gene: CDKD-2

Interactor 2: CKS2 (Q9SJJ5)
Cyclin-dependent kinases regulatory subunit 2
Gene: CKS2

Species: Arabidopsis thaliana

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	20407024
Identification Methods	protein complementation assay
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	CKS~Pkinase
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0007049 - cell cycle GO:0051301 - cell division
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 348 At			1 83
+	At
		188163 CDKD2_ARATH (1-348): 2.49e-150: 428: 100.00		CKS1_ARATH (1-71): 3.17e-40: 128: 94.37
+	At
		1321299 CDKD1_ARATH (5-348): 4.84e-139: 401: 69.48		CKS2_ARATH (1-83): 4.33e-45: 141: 100.00
+	At
		1338686 CDKD3_ARATH (3-346): 8.94e-137: 395: 68.61		CKS2_ARATH (1-83): 4.33e-45: 141: 100.00
+	At
		188168 CDKD3_ARATH (3-346): 8.94e-137: 395: 68.61		CKS1_ARATH (1-71): 3.17e-40: 128: 94.37
+	At
		621728 CDKA1_ARATH (10-296): 5.71e-133: 382: 49.14		CKS2_ARATH (1-83): 4.33e-45: 141: 100.00
+	Hs
		625283 CDK2_HUMAN (10-299): 2.24e-142: 406: 46.92		CKS1_HUMAN (3-76): 1.1e-35: 117: 67.57
+	Hs
		625164 CDK2_HUMAN (10-299): 2.24e-142: 406: 46.92		CKS2_HUMAN (3-76): 4.6e-34: 113: 66.22
+	Hs
		895413 CDK3_HUMAN (10-295): 6.94e-140: 400: 49.31		CKS1_HUMAN (3-76): 1.1e-35: 117: 67.57
+	Hs
		706796 CDK3_HUMAN (10-295): 6.94e-140: 400: 49.31		CKS2_HUMAN (3-76): 4.6e-34: 113: 66.22
+	At
		188136 CDKA1_ARATH (10-296): 5.71e-133: 382: 49.14		CKS1_ARATH (1-71): 3.17e-40: 128: 94.37
+	Dm
		618415 CDK1_DROME (10-297): 5.78e-133: 382: 42.27		Q9VHN1_DROME (2-71): 2.92e-37: 121: 65.71
+	Hs
		414843 CDK1_HUMAN (10-297): 6.46e-134: 385: 46.39		CKS1_HUMAN (3-76): 1.1e-35: 117: 67.57
+	Hs
		895414 CDK5_HUMAN (10-299): 1.02e-133: 384: 46.58		CKS1_HUMAN (3-76): 1.1e-35: 117: 67.57
+	At
		188157 CKB22_ARATH (10-300): 1.33e-128: 372: 41.53		CKS1_ARATH (1-71): 3.17e-40: 128: 94.37
+	Dm
		618471 CDK2_DROME (10-295): 2.27e-131: 379: 44.60		Q9VHN1_DROME (2-71): 2.92e-37: 121: 65.71
+	Hs
		414778 CDK1_HUMAN (10-297): 6.46e-134: 385: 46.39		CKS2_HUMAN (3-76): 4.6e-34: 113: 66.22
+	Sp
		383445 CDK1_SCHPO (10-297): 9.24e-133: 382: 43.43		CKS1_SCHPO (1-80): 1.02e-34: 115: 46.07
+	Dm
		618387 CDK1_DROME (10-297): 5.78e-133: 382: 42.27		CKS1_DROME (3-71): 4.92e-35: 115: 68.12
+	Hs
		706797 CDK5_HUMAN (10-299): 1.02e-133: 384: 46.58		CKS2_HUMAN (3-76): 4.6e-34: 113: 66.22
+	Dm
		618437 CDK2_DROME (10-295): 2.27e-131: 379: 44.60		CKS1_DROME (3-71): 4.92e-35: 115: 68.12