Interactor 1: MED21 (Q9CQ39)
Mediator of RNA polymerase II transcription subunit 21 (Mediator complex subunit 21) (RNA polymerase II holoenzyme component SRB7) (RNAPII complex component SRB7)
Gene: MED21

Interactor 2: MED7 (Q9CZB6)
Mediator of RNA polymerase II transcription subunit 7 (Cofactor required for Sp1 transcriptional activation subunit 9) (CRSP complex subunit 9) (Mediator complex subunit 7)
Gene: MED7

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 9671713
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Med21~Med7
Common GO terms GO:0000151 - ubiquitin ligase complex
GO:0003712 - transcription coregulator activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006357 - regulation of transcription by RNA polymerase II
and 7 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 144
Mm

1 233
+ Hs
+ Dm
+ Ce
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024