HitPredict

Interactor 1: RING2 (Q9CQJ4)
E3 ubiquitin-protein ligase RING2 (EC 2.3.2.27) (RING finger protein 1B) (RING1b) (RING finger protein 2) (RING-type E3 ubiquitin transferase RING2)
Gene: Rnf2

Interactor 2: PHC2 (Q9QWH1)
Polyhomeotic-like protein 2 (mPH2) (Early development regulatory protein 2) (p36)
Gene: PHC2

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.92 0.60 0.745

The method score is based on:

Property Details
Experiments 16024804, 17296600, 20471950, 22496869, 9627119, 12183370, 16359901
Identification Methods affinity chromatography technology, two hybrid, pull down, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000792 - heterochromatin
GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0008270 - zinc ion binding
GO:0035102 - PRC1 complex
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 336
Mm

1 850
+ Hs
+ Mm
+ Hs
+ Dr
+ Mm
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Dm
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024