HitPredict

Interactor 1: FXL20 (Q9CZV8)
F-box/LRR-repeat protein 20 (F-box and leucine-rich repeat protein 20) (F-box/LRR-repeat protein 2-like)
Gene: Fbxl20

Interactor 2: SKP1 (Q9WTX5)
S-phase kinase-associated protein 1 (Cyclin-A/CDK2-associated protein p19) (S-phase kinase-associated protein 1A) (p19A) (p19skp1)
Gene: SKP1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	17803915
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	F-box-like~Skp1
Common GO terms	GO:0005737 - cytoplasm GO:0019005 - SCF ubiquitin ligase complex GO:0031146 - SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 436 Mm			1 163
+	Hs
		929033 FXL20_HUMAN (1-436): 1.72e-94: 292: 99.77		SKP1_HUMAN (1-163): 5.9e-91: 263: 99.39
+	Hs
		929111 FBXL2_HUMAN (14-436): 2.83e-82: 261: 77.78		SKP1_HUMAN (1-163): 5.9e-91: 263: 99.39
+	Ce
		105464 FBXL_CAEEL (20-436): 2.29e-76: 247: 49.40		SKR1_CAEEL (4-162): 1.3e-80: 237: 70.81
+	Mm
		58200 FXL16_MOUSE (30-409): 1.58e-46: 168: 26.55		SKP1_MOUSE (1-163): 3.56e-91: 263: 100.00
+	Hs
		928987 FBXL6_HUMAN (21-421): 4.4e-46: 168: 20.69		SKP1_HUMAN (1-163): 5.9e-91: 263: 99.39
+	Hs
		929099 FBXL7_HUMAN (194-436): 3.65e-32: 129: 26.09		SKP1_HUMAN (1-163): 5.9e-91: 263: 99.39
+	At
		1323395 FBL16_ARATH (25-434): 1.41e-44: 164: 20.68		SKP1B_ARATH (3-162): 3.47e-71: 213: 55.56
+	At
		1107660 AFB3_ARATH (28-406): 8.97e-37: 143: 20.25		SKP1A_ARATH (3-162): 6.66e-73: 217: 57.76
+	At
		1123017 TIR1_ARATH (21-408): 1.78e-32: 131: 18.78		ASK4_ARATH (4-162): 1.96e-75: 223: 52.80
+	At
		1123022 TIR1_ARATH (21-408): 1.78e-32: 131: 18.78		ASK3_ARATH (4-162): 9.49e-74: 219: 50.31
+	At
		1107595 EBF2_ARATH (39-435): 9.3e-33: 132: 22.30		SKP1A_ARATH (3-162): 6.66e-73: 217: 57.76
+	At
		1107590 TIR1_ARATH (21-408): 1.78e-32: 131: 18.78		SKP1A_ARATH (3-162): 6.66e-73: 217: 57.76
+	At
		1173681 EBF2_ARATH (39-435): 9.3e-33: 132: 22.30		SKP1B_ARATH (3-162): 3.47e-71: 213: 55.56
+	At
		221646 EBF2_ARATH (39-435): 9.3e-33: 132: 22.30		ASK11_ARATH (4-162): 3.36e-71: 213: 55.35
+	At
		1123015 TIR1_ARATH (21-408): 1.78e-32: 131: 18.78		SKP1B_ARATH (3-162): 3.47e-71: 213: 55.56
+	At
		221642 TIR1_ARATH (21-408): 1.78e-32: 131: 18.78		ASK11_ARATH (4-162): 3.36e-71: 213: 55.35
+	At
		249956 EBF2_ARATH (39-435): 9.3e-33: 132: 22.30		ASK12_ARATH (4-162): 7.7e-70: 209: 54.09
+	At
		1123019 TIR1_ARATH (21-408): 1.78e-32: 131: 18.78		ASK9_ARATH (3-162): 1.41e-69: 208: 47.83
+	At
		1173682 EBF2_ARATH (39-435): 9.3e-33: 132: 22.30		ASK13_ARATH (4-162): 5.54e-66: 200: 47.21
+	At
		286188 EBF2_ARATH (39-435): 9.3e-33: 132: 22.30		ASK14_ARATH (3-162): 3.46e-63: 192: 48.45