HitPredict

Interactor 1: Q9DCC5 (Q9DCC5)
Cbx3 protein (Chromobox 3)
Gene: Cbx3

Interactor 2: EHMT2 (Q9Z148)
Histone-lysine N-methyltransferase EHMT2 (EC 2.1.1.-) (EC 2.1.1.367) (Euchromatic histone-lysine N-methyltransferase 2) (HLA-B-associated transcript 8) (Histone H3-K9 methyltransferase 3) (H3-K9-HMTase 3) (Protein G9a)
Gene: EHMT2

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	25680957, 29795351
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 183 Mm			1 1263
+	Mm
		1143050 CBX5_MOUSE (11-182): 1.21e-55: 175: 59.89		EHMT2_MOUSE (1-1263): 0: 985: 100.00
+	Hs
		1027194 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		EHMT2_HUMAN (78-1263): 0: 867: 94.97
+	Hs
		800497 CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89		EHMT2_HUMAN (78-1263): 0: 867: 94.97
+	Hs
		949863 CBX1_HUMAN (36-180): 1.02e-53: 170: 71.33		EHMT2_HUMAN (78-1263): 0: 867: 94.97
+	Hs
		1027268 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		EHMT1_HUMAN (80-1259): 0: 656: 47.87
+	Mm
		1125433 Q9DCC5_MOUSE (1-183): 1.62e-71: 215: 100.00		EHMT1_MOUSE (64-1259): 0: 645: 44.76
+	Hs
		800530 CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89		EHMT1_HUMAN (80-1259): 0: 656: 47.87
+	Hs
		949889 CBX1_HUMAN (36-180): 1.02e-53: 170: 71.33		EHMT1_HUMAN (80-1259): 0: 656: 47.87
+	Hs
		203674 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		SUV91_HUMAN (914-1230): 8.33e-88: 293: 31.53
+	Hs
		1027262 CBX3_HUMAN (1-183): 1.62e-71: 215: 100.00		SUV92_HUMAN (988-1230): 4.56e-86: 288: 36.50
+	Mm
		222468 Q9DCC5_MOUSE (1-183): 1.62e-71: 215: 100.00		SUV91_MOUSE (987-1230): 7.05e-85: 285: 35.40
+	Mm
		222460 CBX3_MOUSE (1-183): 4.67e-71: 214: 99.45		SUV91_MOUSE (987-1230): 7.05e-85: 285: 35.40
+	Mm
		613035 CBX3_MOUSE (1-183): 4.67e-71: 214: 99.45		SUV92_MOUSE (988-1230): 4.71e-83: 281: 36.88
+	Hs
		203638 CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89		SUV91_HUMAN (914-1230): 8.33e-88: 293: 31.53
+	Hs
		203823 V9HWG0_HUMAN (11-182): 1.62e-55: 175: 59.89		SUV91_HUMAN (914-1230): 8.33e-88: 293: 31.53
+	Hs
		1331984 V9HWG0_HUMAN (11-182): 1.62e-55: 175: 59.89		SUV92_HUMAN (988-1230): 4.56e-86: 288: 36.50
+	Hs
		203662 CBX1_HUMAN (36-180): 1.02e-53: 170: 71.33		SUV91_HUMAN (914-1230): 8.33e-88: 293: 31.53
+	Hs
		800527 CBX5_HUMAN (11-182): 1.62e-55: 175: 59.89		SUV92_HUMAN (988-1230): 4.56e-86: 288: 36.50
+	Mm
		222467 CBX5_MOUSE (11-182): 1.21e-55: 175: 59.89		SUV91_MOUSE (987-1230): 7.05e-85: 285: 35.40
+	Hs
		949887 CBX1_HUMAN (36-180): 1.02e-53: 170: 71.33		SUV92_HUMAN (988-1230): 4.56e-86: 288: 36.50