HitPredict

Interactor 1: LST8 (Q9DCJ1)
Target of rapamycin complex subunit LST8 (TORC subunit LST8) (G protein beta subunit-like) (Protein GbetaL) (Mammalian lethal with SEC13 protein 8) (mLST8)
Gene: Mlst8

Interactor 2: MTOR (Q9JLN9)
Serine/threonine-protein kinase mTOR (EC 2.7.11.1) (FK506-binding protein 12-rapamycin complex-associated protein 1) (FKBP12-rapamycin complex-associated protein) (Mammalian target of rapamycin) (mTOR) (Mechanistic target of rapamycin) (Rapamycin target protein 1) (RAPT1)
Gene: MTOR

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.83 1.00 0.916

The method score is based on:

Property Details
Experiments 18851840, 27340174, 36927703, 20801936, 18505677
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PI3_PI4_kinase~WD40
Common GO terms GO:0005737 - cytoplasm
GO:0005765 - lysosomal membrane
GO:0006974 - DNA damage response
GO:0007010 - cytoskeleton organization
GO:0010507 - negative regulation of autophagy
and 14 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 326
Mm

1 2549
+ Hs
+ Hs
+ Dm
+ Sc
+ Sc
+ Sp
+ At
+ At
+ Sp
+ Hs
+ Hs
+ Hs
+ Sp
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024