Interactor 1: ASC (Q9EPB4)
Apoptosis-associated speck-like protein containing a CARD (mASC) (PYD and CARD domain-containing protein)
Gene: Pycard

Interactor 2: ASC (Q9EPB4)
Apoptosis-associated speck-like protein containing a CARD (mASC) (PYD and CARD domain-containing protein)
Gene: Pycard

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 1.00 0.830

The method score is based on:

Property Details
Experiments 24407287, 25847972, 35110683
Identification Methods affinity chromatography technology, biochemical, cross-linking study
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains CARD~CARD, PYRIN~PYRIN
Common GO terms GO:0000139 - Golgi membrane
GO:0002020 - protease binding
GO:0002218 - activation of innate immune response
GO:0002221 - pattern recognition receptor signaling pathway
GO:0002230 - positive regulation of defense response to virus by host
and 75 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 193
Mm

1 193
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+ Dr
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024