HitPredict

Interactor 1: VP241 (Q9FFB3)
Vacuolar protein sorting-associated protein 24 homolog 1 (AtVPS24-1) (Charged multivesicular body protein 3 homolog 1) (ESCRT-III complex subunit VPS24 homolog 1)
Gene: VPS24-1

Interactor 2: VP202 (Q9FY89)
Vacuolar protein sorting-associated protein 20 homolog 2 (AtVPS20-2) (Charged multivesicular body protein 6 homolog 2) (ESCRT-III complex subunit VPS20 homolog 2)
Gene: VPS20.2

Species: Arabidopsis thaliana

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.48	1.00	0.698

Property	Details
Experiments	21442383
Identification Methods	protein complementation assay, bimolecular fluorescence complementation
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Snf7~Snf7
Common GO terms	GO:0000815 - ESCRT III complex GO:0005770 - late endosome GO:0005771 - multivesicular body GO:0005829 - cytosol GO:0015031 - protein transport and 1 others more... GO:0070676 - intralumenal vesicle formation
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 229 At			1 216
+	At
		98407 VP241_ARATH (1-229): 4.66e-50: 164: 100.00		F4JXR3_ARATH (1-215): 1.27e-45: 154: 16.17
+	Ce
		1090380 Q9U2F6_CAEEL (7-228): 3.93e-53: 172: 23.71		Q18886_CAEEL (2-209): 1.62e-40: 139: 23.47
+	At
		1322582 VP241_ARATH (1-229): 4.66e-50: 164: 100.00		VP601_ARATH (1-215): 7.4e-43: 146: 17.47
+	At
		1013158 VPS2B_ARATH (5-228): 7.66e-48: 158: 28.13		VP601_ARATH (1-215): 7.4e-43: 146: 17.47
+	At
		1276045 VPS2C_ARATH (5-228): 3.04e-51: 167: 25.89		VP202_ARATH (1-216): 1.13e-39: 137: 100.00
+	At
		1322583 VP241_ARATH (1-229): 4.66e-50: 164: 100.00		VPS2A_ARATH (1-206): 3.46e-37: 131: 14.01
+	At
		1209623 VPS2C_ARATH (5-228): 3.04e-51: 167: 25.89		VP201_ARATH (1-216): 6.32e-36: 127: 85.07
+	At
		1276050 VPS2C_ARATH (5-228): 3.04e-51: 167: 25.89		VP322_ARATH (1-216): 2.45e-35: 126: 24.54
+	At
		1013164 VPS2A_ARATH (6-228): 8.94e-55: 176: 25.56		VPS2B_ARATH (3-213): 3.29e-31: 115: 10.38
+	At
		1209625 VP241_ARATH (1-229): 4.66e-50: 164: 100.00		VP201_ARATH (1-216): 6.32e-36: 127: 85.07
+	Sc
		732845 DID4_YEAST (7-228): 2.79e-53: 173: 25.56		SNF7_YEAST (6-205): 3.97e-32: 118: 25.24
+	At
		1322584 VP241_ARATH (1-229): 4.66e-50: 164: 100.00		VP322_ARATH (1-216): 2.45e-35: 126: 24.54
+	At
		287069 VPS2C_ARATH (5-228): 3.04e-51: 167: 25.89		VP321_ARATH (1-202): 3.35e-33: 120: 22.12
+	Sc
		732861 DID4_YEAST (7-228): 2.79e-53: 173: 25.56		VPS20_YEAST (6-211): 1.27e-30: 114: 28.44
+	At
		1013168 VPS2B_ARATH (5-228): 7.66e-48: 158: 28.13		VP322_ARATH (1-216): 2.45e-35: 126: 24.54
+	At
		287071 VP241_ARATH (1-229): 4.66e-50: 164: 100.00		VP321_ARATH (1-202): 3.35e-33: 120: 22.12
+	At
		287066 VPS2B_ARATH (5-228): 7.66e-48: 158: 28.13		VP321_ARATH (1-202): 3.35e-33: 120: 22.12
+	At
		1013141 VPS2B_ARATH (5-228): 7.66e-48: 158: 28.13		VPS2B_ARATH (3-213): 3.29e-31: 115: 10.38
+	Sc
		732860 DID4_YEAST (7-228): 2.79e-53: 173: 25.56		VPS60_YEAST (1-209): 8.02e-23: 93.7: 20.35