HitPredict

Interactor 1: CPSF1 (Q9FGR0)
Cleavage and polyadenylation specificity factor subunit 1 (Cleavage and polyadenylation specificity factor 160 kDa subunit) (AtCPSF160) (CPSF 160 kDa subunit)
Gene: CPSF160

Interactor 2: CPSF2 (Q9LKF9)
Cleavage and polyadenylation specificity factor subunit 2 (Cleavage and polyadenylation specificity factor 100 kDa subunit) (AtCPSF100) (CPSF 100 kDa subunit) (Protein EMBRYO DEFECTIVE 1265) (Protein ENHANCED SILENCING PHENOTYPE 5)
Gene: CPSF100

Species: Arabidopsis thaliana

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.83	0.60	0.707

Property	Details
Experiments	16897494, 18479511, 17008405, 19748916
Identification Methods	pull down, two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005847 - mRNA cleavage and polyadenylation specificity factor complex
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1442 At			1 739
+	At
		1320907 CPSF1_ARATH (1-1442): 0: 1368: 100.00		CPSF3_ARATH (2-648): 0: 560: 20.30
+	At
		1208877 CPSF1_ARATH (1-1442): 0: 1368: 100.00		CPS3B_ARATH (4-624): 2.93e-175: 517: 19.18
+	Hs
		1014211 CPSF1_HUMAN (3-1442): 0: 1128: 30.07		CPSF2_HUMAN (1-739): 0: 695: 36.74
+	Hs
		1014217 CPSF1_HUMAN (3-1442): 0: 1128: 30.07		CPSF3_HUMAN (2-651): 0: 580: 18.55
+	Sp
		251783 CFT1_SCHPO (59-1442): 0: 886: 21.68		CFT2_SCHPO (23-739): 0: 539: 30.42
+	Sp
		142956 CFT1_SCHPO (59-1442): 0: 886: 21.68		YSH1_SCHPO (2-513): 1.01e-153: 466: 22.54
+	Sc
		986638 CFT1_YEAST (60-1442): 0: 750: 15.39		YSH1_YEAST (2-646): 2.08e-163: 492: 19.70
+	Sc
		988501 CFT1_YEAST (60-1442): 0: 750: 15.39		CFT2_YEAST (11-737): 2.87e-147: 453: 21.08