HitPredict

Interactor 1: CAC1A (O00555)
Voltage-dependent P/Q-type calcium channel subunit alpha-1A (Brain calcium channel I) (BI) (Calcium channel, L type, alpha-1 polypeptide isoform 4) (Voltage-gated calcium channel subunit alpha Cav2.1)
Gene: CACNA1A

Interactor 2: LTBP4 (Q8N2S1)
Latent-transforming growth factor beta-binding protein 4 (LTBP-4)
Gene: LTBP4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.50	0.504

Property	Details
Experiments	21078624
Identification Methods	two hybrid, pull down
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 2506 Hs			1 1624
+	Hs
		132298 CAC1A_HUMAN (1-2506): 0: 1897: 100.00		NOTC1_HUMAN (1220-1624): 1.98e-22: 107: 13.06
+	Hs
		132290 CAC1A_HUMAN (1-2506): 0: 1897: 100.00		FBLN1_HUMAN (549-742): 2.84e-22: 105: 36.23
+	Hs
		132361 CAC1A_HUMAN (1-2506): 0: 1897: 100.00		JAG2_HUMAN (1208-1624): 2.04e-21: 104: 13.71
+	Hs
		132314 CAC1A_HUMAN (1-2506): 0: 1897: 100.00		LTBP1_HUMAN (27-632): 1.44e-17: 91.7: 15.22
+	Hs
		82701 CAC1A_HUMAN (1-2506): 0: 1897: 100.00		B9EG76_HUMAN (24-587): 8.48e-16: 85.5: 14.56
+	Hs
		132274 CAC1A_HUMAN (1-2506): 0: 1897: 100.00		MEGF6_HUMAN (17-340): 2.96e-13: 77.4: 10.47
+	Hs
		126309 CAC1A_HUMAN (1-2506): 0: 1897: 100.00		MATN2_HUMAN (281-524): 5.95e-13: 76.2: 13.89
+	Hs
		81920 CAC1A_HUMAN (1-2506): 0: 1897: 100.00		B7ZLY3_HUMAN (25-671): 4.91e-12: 73.6: 9.27
+	Hs
		132356 CAC1A_HUMAN (1-2506): 0: 1897: 100.00		LTBP3_HUMAN (14-538): 3.31e-10: 67.4: 11.74
+	Hs
		1047292 CAC1C_HUMAN (1129-1934): 1.84e-95: 348: 18.82		CELR3_HUMAN (301-393): 4.96e-09: 63.6: 16.50
+	Dm
		422755 CAC1D_DROME (1194-1544): 1.16e-38: 162: 22.79		NOTCH_DROME (1325-1623): 2.63e-16: 87.8: 10.42